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VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis

Fatima Rizvi, Yu-Ri Lee, Ricardo Diaz-Aragon, et al.



Selected by Organogenesis and Cancer Program

Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing

Fumiyuki Hatanaka, Keiichiro Suzuki, Kensaku Shojima, et al.



Selected by Preethi Krishnaraj

Neuronal activity drives pathway-specific depolarization of astrocyte distal processes

Moritz Armbruster, Saptarnab Naskar, Jacqueline Garcia, et al.



Selected by Kristina Kuhbandner

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.



Selected by Idoia Quintana-Urzainqui

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins



Selected by Kirsty Ferguson

Oligodendrocyte-derived exosomes promote axonal transport and axonal long-term maintenance

Carsten Frühbeis, Wen Ping Kuo-Elsner, Kerstin Barth, et al.



Selected by Theresa Pohlkamp

ROS production by localized SCHENGEN receptor module drives lignification at subcellular precision

Satoshi Fujita, Damien De Bellis, Kai H. Edel, et al.



Selected by Marc Somssich

Optogenetic control of Wnt signaling for modeling early embryogenic patterning with human pluripotent stem cells

Nicole A. Repina, Xiaoping Bao, Joshua A. Zimmermann, et al.



Selected by Pavithran Ravindran

Prospective, brain-wide labeling of neuronal subclasses with enhancer-driven aavs

Lucas T Graybuck, Adriana Sedeño-Cortés, Thuc Nghi Nguyen, et al.



Selected by Jesus Victorino

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T Riglar, David L Richmond, Laurent Potvin-Trottier, et al.



Selected by Meng Zhu

A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spider Parasteatoda tepidariorum

Christian L. B. Paese, Anna Schoenauer, Daniel J. Leite, et al.



Selected by Erik Clark

Germ layer specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm.

Miguel Salinas-Saavedra, Amber Q. Rock, Mark Q. Martindale



Selected by Claire Simon & Sophie Morgani

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