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Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience

John W. Brooks, Vikas Tillu, Suzie Verma, et al.

The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination

Alejandra J.H. Cabrera, Barry M. Gumbiner, Young V. Kwon

Discussion

Membrane architecture and adherens junctions contribute to strong Notch pathway activation

Julia Falo-Sanjuan, Sarah J. Bray

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Ion Andreu, Bryan Falcones, Sebastian Hurst, et al.

Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion

Anh Phuong Le, Jean-François Rupprecht, René-Marc Mège, et al.

Discussion

An early cell shape transition drives evolutionary expansion of the human forebrain

Silvia Benito-Kwiecinski, Stefano L. Giandomenico, Magdalena Sutcliffe, et al.

Epithelial Tissues as Active Solids: From Nonlinear Contraction Pulses to Rupture Resistance

Shahaf Armon, Matthew S. Bull, Avraham Moriel, et al.

Discussion

Mechanics regulate human embryonic stem cell self-organization to specify mesoderm

Jonathon M. Muncie, Nadia M.E. Ayad, Johnathon N. Lakins, et al.

Stem-cell niche self-restricts the signaling range via receptor-ligand degradation

Sophia Ladyzhets, Matthew Antel, Taylor Simao, et al.

Discussion

Robustness of epithelial sealing is an emerging property of local ERK feedbacks driven by cell elimination

Léo Valon, Florence Levillayer, Anđela Davidović, et al.

Assembly of a persistent apical actin network by the formin Frl/Fmnl tunes epithelial cell deformability

Benoit Dehapiot, Raphaël Clément, Gabriella Gazsó-Gerhát, et al.

Microtubules stabilize intercellular contractile force transmission during tissue folding

Discussion