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Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Biochemistry

Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neurons

Klaudia Strucinska, Parker Kneis, Travis Pennington, et al.

Selected by 11 February 2025

Felipe Del Valle Batalla

Cell Biology

Visually-guided compensation of deafening-induced song deterioration

M Rolland, A Zai, RHR Hahnloser, et al.

Selected by 04 February 2025

Maitri Manjunath

Animal Behavior and Cognition

Mechanical stresses govern myoblast fusion and myotube growth

Yoann Le Toquin, Sushil Dubey, Aleksandra Ardaševa, et al.

Selected by 29 January 2025

Vibha SINGH, Prasanna Padmanaban

Cell Biology

IMMClock reveals immune aging and T cell function at single-cell resolution

Yael Gurevich Schmidt, Di Wu, Sanna Madan, et al.

Selected by 19 January 2025

Jessica Chevallier

Bioinformatics

Thermal preconditioning modulates coral physiology and heat tolerance: A multi-species perspective

Erik F. Ferrara, Anna Roik, Franziska Wöhrmann-Zipf, et al.

Selected by 14 January 2025

Jasmine Talevi

Physiology

Adenine DNA methylation associated to transcription is widespread across eukaryotes

Pedro Romero Charria, Cristina Navarrete, Vladimir Ovchinnikov, et al.

Selected by 13 January 2025

Francisco Falcon

Evolutionary Biology

Sex chromosomes shape the transcriptional landscape of the preimplantation mouse embryo

Daniel M. Snell, Wazeer Varsally, Aurélien Courtois, et al.

Selected by 11 January 2025

Mansi

Developmental Biology

Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models

Nalini R. Rao, Olivia DeGulis, Toshihiro Nomura, et al.

Selected by 11 January 2025

Jawdat Sandakly

Neuroscience

Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation

Winanto, Li-Yi Tan, Wai Hon Chooi, et al.

Selected by 08 January 2025

Manuel Lessi

Neuroscience

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Zhipeng Deng, Camila B. Tovani, Simona Bianco, et al.

Selected by 06 January 2025

Castro Johnbosco

Bioengineering

Target cell tension regulates macrophage trogocytosis

Caitlin E. Cornell, Aymeric Chorlay, Deepak Krishnamurthy, et al.

Selected by 04 January 2025

Felipe Del Valle Batalla

Biophysics