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amyotrophic lateral sclerosis associated mislocalisation of TDP-43 to the cytoplasm causes cortical hyperexcitability and reduced excitatory neurotransmission in the motor cortex

MS Dyer, KE Lewis, AK Walker, et al.

Selected by 01 August 2020

Kristina Kuhbandner

Neuroscience

FUS gene is dual-coding with both proteins united in FUS-mediated toxicity

Marie A. Brunet, Jean-Francois Jacques, Sonya Nassari, et al.

Selected by 12 May 2020

Madhuja Samaddar

Molecular Biology

Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease

Richard J. Wheeler, Hyun O. Lee, Ina Poser, et al.

Selected by 30 August 2019

Madhuja Samaddar

Cell Biology

Generalized displacement of DNA- and RNA-binding factors mediates the toxicity of arginine-rich cell-penetrating peptides

V. Lafarga, O. Sirozh, I. Díaz-López, et al.

Selected by 30 July 2019

Emily Graves

Neuroscience

Molecularly distinct cores coexist inside stress granules

Luca Cirillo, Adeline Cieren, Monica Gotta

Selected by 13 June 2019

Tessa Sinnige

Cell Biology

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

AND

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

Selected by 12 September 2018

Yen-Chung Chen

Systems Biology

OptoGranules reveal the evolution of stress granules to ALS-FTD pathology

Peipei Zhang, Baochang Fan, Peiguo Yang, et al.

Selected by 07 July 2018

Srivats Venkataramanan

Neuroscience