Search results

Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Discussion

Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Jasmin Kaivola, Karolina Punovuori, Megan R. Chastney, et al.

Selected by 19 December 2024

Teodora Piskova

Discussion

Impaired 26S proteasome causes learning and memory deficiency and induces neuroinflammation mediated by NF-κB in mice

Christa C. Huber, Eduardo Callegari, Maria Paez, et al.

Selected by 22 August 2024

Gustavo Stelzer, Marcus Oliveira

Discussion

Cell cycle-dependent mRNA localization in P-bodies

Adham Safieddine, Marie-Noëlle Benassy, Thomas Bonte, et al.

Selected by 11 July 2024

Mohammed JALLOH

Discussion

Light-microscopy based dense connectomic reconstruction of mammalian brain tissue

Mojtaba R. Tavakoli, Julia Lyudchik, Michał Januszewski, et al.

Selected by 10 June 2024

Cemre Coskun

G6b-B antibody-based cis-acting platelet receptor inhibitors (CAPRIs) as a new family of anti-thrombotic therapeutics

Alexandra Mazharian, Ophélie Bertin, Amrita Sarkar, et al.

Selected by 03 June 2024

Simon Cleary

Lytic bacteriophages interact with respiratory epithelial cells and induce the secretion of antiviral and proinflammatory cytokines

Paula F. Zamora, Thomas G. Reidy, Catherine R. Armbruster, et al.

Selected by 20 May 2024

UofA IMB565 et al.

Discussion

Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion

David Anaguano, Opeoluwa Adewale-Fasoro, Grace S. Vick, et al.

Selected by 03 April 2024

Sara Chelaghma

Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma

Yoshiaki Yasumizu, Makoto Kinoshita, Martin Jinye Zhang, et al.

Selected by 27 March 2024

Jessica Chevallier

Discussion

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.

Selected by 22 December 2023

Jade Chan

Discussion

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by 29 November 2023

Benjamin Dominik Maier

Glycan-specific IgM is critical for human immunity to Staphylococcus aureus

Astrid Hendriks, Priscilla F. Kerkman, Meri R.J. Varkila, et al.

Selected by 10 August 2023

Lucy Bowden

Discussion