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Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

Selected by 18 June 2020

Zhang-He Goh

Pharmacology and Toxicology

Phage infection mediates inhibition of bystander bacteria

Anushila Chatterjee, Julia L. E. Willett, Gary M. Dunny, et al.

Selected by 31 May 2020

Josie Gibson

Microbiology

Anti-biofilm efficacy of a medieval treatment for bacterial infection requires the combination of multiple ingredients

Jessica Furner-Pardoe, Blessing O Anonye, Ricky Cain, et al.

AND

The safety profile of Bald’s eyesalve for the treatment of bacterial infections

Blessing O Anonye, Valentine Nweke, Jessica Furner-Pardoe, et al.

Selected by 26 May 2020

Snehal Kadam

Microbiology

The antimicrobial peptide DGL13K is active against resistant gram-negative bacteria and subinhibitory concentrations stimulate bacterial growth without causing resistance

Sven-Ulrik Gorr, Hunter V. Brigman, Jadyn C. Anderson, et al.

Selected by 17 May 2020

Zhang-He Goh

Pharmacology and Toxicology

Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance

Michael M. Maiden, Christopher M. Waters

Selected by 27 April 2020

Amberley Stephens

Microbiology

Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts

J. Stone Doggett, Tracey Schultz, Alyssa J. Miller, et al.

Selected by 10 April 2020

Zhang-He Goh

Pharmacology and Toxicology

Combining antibiotics with antivirulence compounds is effective and can reverse selection for antibiotic resistance in Pseudomonas aeruginosa

Chiara Rezzoagli, Martina Archetti, Michael Baumgartner, et al.

Selected by 10 December 2019

Zhang-He Goh

Pharmacology and Toxicology

Engineering Phage Host-Range and Suppressing Bacterial resistance Through Phage Tail Fiber Mutagenesis

Kevin Yehl, Sébastien Lemire, Andrew C. Yang, et al.

Selected by 27 July 2019

Zhang-He Goh

Synthetic Biology

antimicrobials: Discovery, clinical use, and development of resistance

Preprints that describe the discovery of new antimicrobials and any improvements made regarding their clinical use. Includes preprints that detail the factors affecting antimicrobial selection and the development of antimicrobial resistance.

 



List by Zhang-He Goh

Using machine learning to guide targeted and locally-tailored empiric antibiotic prescribing in a children's hospital in Cambodia

Mathupanee Oonsivilai, Mo Yin, Nantasit Luangasanatip, et al.

Selected by 22 July 2018

Zhang-He Goh

Epidemiology

Repurposing the quinoline antibiotic nitroxoline to treat infections caused by the brain-eating amoeba Balamuthia mandrillaris

Matthew T. Laurie, Corin V. White, Hanna Retallack, et al.

Selected by 11 July 2018

Zhang-He Goh

Pharmacology and Toxicology