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Applications, Promises, and Pitfalls of Deep Learning for Fluorescence Image Reconstruction

Chinmay Belthangady , Loic A. Royer

Discussion

Embryo geometry drives formation of robust signaling gradients through receptor localization

Zhechun Zhang, Steven Zwick, Ethan Loew, et al.

Proteomic Studies reveal Disrupted in Schizophrenia 1 as a key regulator unifying neurodevelopment and synaptic function

Adriana Ramos, Carmen Rodriguez-Seoane, Isaac Rosa, et al.

Discussion

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pigmentation pathway

Alexander Swoboda, Robert Soukup, Katharina Kinslechner, et al.

Discussion

Arterio-Venous Remodeling in the Zebrafish Trunk Is Controlled by Genetic Programming and Flow-Mediated Fine-Tuning

Ilse Geudens, Baptiste Coxam, Silvanus Alt, et al.

Discussion

Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

Kerstin Klinkert, Nicolas Levernier, Peter Gross, et al.

AND

Centrosome Aurora A gradient ensures a single PAR-2 polarity axis by regulating RhoGEF ECT-2 localization in C. elegans embryos

Sachin Kotak, Sukriti Kapoor

Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

Amber N Stratman, Olivia M Farrelly, Constantinos M Mikelis, et al.

Discussion

The creation of sexual dimorphism in Drosophila gonad stem cell niches

Nicole Camara, Cale Whitworth, Mark Van Doren

Excitable RhoA dynamics drive pulsed contractions in the early C. elegans embryo.

Jonathan B Michaux, Francois B Robin, William M McFadden, et al.

Discussion

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages is necessary for functional spinal cord regeneration in zebrafish

Themistoklis M. Tsarouchas, Daniel Wehner, Leonardo Cavone, et al.

Nuclear pore density controls heterochromatin reorganization during senescence

Charlene Boumendil, Priya Hari, Karl Olsen, et al.

A minimal "push-pull" bistability model explains oscillations between quiescent and proliferative cell states.

Sandeep Krishna, Sunil Laxman