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organoids reveal niche-specific mechanotransduction-guided human cortical patterning and cell fate acquisition.

Alex J. Kingston, Annabelle A. M. Wurmser, Aditi S. Kulkarni, et al.

Selected by 19 August 2026

Kanishka Parashar

Cell Biology

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Selected by 17 March 2026

Dina Kabbara

Pharmacology and Toxicology

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Selected by 27 October 2025

Manuel Lessi, Riccardo Nagni

Neuroscience

Identification of neuron-glia signaling feedback in human schizophrenia using patient-derived, mix-and-match forebrain assembloids

Eunjee Kim, Yunhee Kim, Soojung Hong, et al.

Selected by 12 June 2025

Justine Gromaire et al.

Neuroscience

Polystyrene nanoplastics promote neurodegeneration by catalyzing TDP43 hyperphosphorylation

Winanto, Li-Yi Tan, Wai Hon Chooi, et al.

Selected by 08 January 2025

Manuel Lessi

Neuroscience

Alzheimer’s Disease Patient brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune organoids for Disease Modeling and Drug Discovery

Yanru Ji, Xiaoling Chen, Meek Connor Joseph, et al.

Selected by 07 November 2024

Manuel Lessi

Neuroscience

Actin-based deformations of the nucleus control multiciliated ependymal cell differentiation

Marianne Basso, Alexia Mahuzier, Syed Kaabir Ali, et al.

Selected by 30 October 2024

Ryan Harrison

Developmental Biology

Fetal brain response to maternal inflammation requires microglia

Bridget Elaine LaMonica Ostrem, Nuria Dominguez Iturza, Jeffrey Stogsdill, et al.

Selected by 24 April 2024

Manuel Lessi

Neuroscience

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

Selected by 04 January 2024

Manuel Lessi

Neuroscience

Generating human neural diversity with a multiplexed morphogen screen in organoids

Neal D. Amin, Kevin W. Kelley, Jin Hao, et al.

Selected by 20 July 2023

Monica Tambalo

Cell Biology

Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness

Dominik Koessinger, David Novo, Anna Koessinger, et al.

Selected by 13 June 2023

Jade Chan

Cancer Biology

Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells

John D. Blair, Austin Hartman, Fides Zenk, et al.

Selected by 19 April 2023

Benjamin Dominik Maier

Molecular Biology