CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
06 September 2023
Jessica Chevallier, Pierre Caron
Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Selected by
05 June 2023
Pierre Caron
EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
15 May 2023
Jennifer Ann Black
Nuclear myosin VI maintains replication fork stability
Selected by
13 December 2022
Pierre Caron
Saturation variant interpretation using CRISPR prime editing
Selected by
20 October 2021
Jeffrey Calhoun
EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break
Selected by
05 January 2021
Sree Rama Chaitanya
ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells
Selected by
31 December 2020
Giuseppina D'Alessandro
A role for RNA and DNA:RNA hybrids in the modulation of DNA repair by homologous recombination
Selected by
19 March 2018
Carmen Adriaens