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Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

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Stem-cell niche self-restricts the signaling range via receptor-ligand degradation

Sophia Ladyzhets, Matthew Antel, Taylor Simao, et al.

Interspecies differences in proteome turnover kinetics are correlated with lifespans and energetic demands

Kyle Swovick, Denis Firsanov, Kevin A. Welle, et al.

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FUS gene is dual-coding with both proteins united in FUS-mediated toxicity

Marie A. Brunet, Jean-Francois Jacques, Sonya Nassari, et al.

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An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma

Rediet Zewdu, Elnaz Mirzaei Mehrabad, Kelley Ingram, et al.

Biophysical forces rewire cell metabolism to guide microtubule-dependent cell mechanics

Stephanie Torrino, Stephane Audebert, Ilyes Belhadj, et al.

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Nuclear myosin VI regulates the spatial organization of mammalian transcription initiation

Yukti Hari-Gupta, Natalia Fili, Ália dos Santos, et al.

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The polyol pathway is a crucial glucose sensor in Drosophila

Hiroko Sano, Akira Nakamura, Mariko Yamane, et al.

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Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Retrospective identification of rare cell populations underlying drug resistance connects molecular variability with cell fate

Benjamin L. Emert, Christopher Coté, Eduardo A. Torre, et al.

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

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Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Özgen Deniz, Mamataz Ahmed, Christopher D. Todd, et al.

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