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Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

Thomas J. Cahill, Xin Sun, Christophe Ravaud, et al.

Selected by 25 August 2020

Jonny Coates

Developmental Biology

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Selected by 11 August 2020

Osvaldo Contreras, Alexander Ward

Cell Biology

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan Jahnel, Nora Papai, et al.

Selected by 20 July 2020

Alok Javali

Developmental Biology

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Selected by 13 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

Zachary D. Aron, Atousa Mehrani, Eric D. Hoffer, et al.

Selected by 18 June 2020

Zhang-He Goh

Pharmacology and Toxicology

Genetic developmental Timing Revealed by Inter-Species Transplantations in Fish

Jana Franziska Fuhrmann, Lorena Buono, Juan Ramón Martinez Morales, et al.

Selected by 06 May 2020

Martin Estermann

Developmental Biology

Depression of heart rate in fish at critically high temperatures is due to atrioventricular block

Jaakko Haverinen, Matti Vornanen

Selected by 26 March 2020

James Marchant

The transcriptional legacy of developmental stochasticity

Sara Ballouz, Maria T. Pena, Frank M. Knight, et al.

Selected by 23 January 2020

Sergio Menchero

Genomics

Over-activation of BMP signaling in neural crest cells precipitates heart outflow tract septation

Jean Francois Darrigrand, Mariana Valente, Pauline Martinez, et al.

Selected by 01 April 2019

Giulia Boezio

Developmental Biology

Functional testing of a human PBX3 variant in zebrafish reveals a potential modifier role in congenital heart defects

Gist H. Farr III, Kimia Imani, Darren Pouv, et al.

Selected by 03 July 2018

Hannah Brunsdon

Genetics

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling

Claudio Cantù, Anastasia Felker, Dario Zimmerli, et al.

Selected by 07 February 2018

Andreas van Impel

Developmental Biology