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Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

Baker N., Catta-Preta C.M.C., Neish R., et al.



Selected by Mariana De Niz

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan



Selected by Connor Rosen

Live-cell imaging shows uneven segregation of extrachromosomal DNA elements and transcriptionally active extrachromosomal DNA clusters in cancer

Eunhee Yi, Amit D. Gujar, Molly Guthrie, et al.



Selected by Sree Rama Chaitanya

High-throughput discovery and characterization of human transcriptional effectors

Josh Tycko, Nicole DelRosso, Gaelen T. Hess, et al.



Selected by Clarice Hong

Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds

Jason Ioannidis, Gunes Taylor, Debiao Zhao, et al.



Selected by Martin Estermann

Generating single-sex litters: development of CRISPR-cas9 genetic tools to produce all-male offspring

Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, et al.



Selected by Martin Estermann

In response to Li et al.: Linker histones function in Drosophila embryogenesis

Albert Carbonell, Lazslo Henn, Juan Pérez-Roldán, et al.



Selected by Sree Rama Chaitanya

Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect splicing



Selected by Nidhi Kanwal

High-content Imaging-based Pooled CRISPR Screens in Mammalian Cells

Xiaowei Yan, Nico Stuurman, Susana A. Ribeiro, et al.

AND

Image-based pooled whole genome CRISPR screening for Parkin and TFEB subcellular localization

Gil Kanfer, Shireen A. Sarraf, Yaakov Maman, et al.



Selected by Kirsty Ferguson

Frizzled-dependent Planar Cell Polarity without Wnt Ligands

Joyce J.S. Yu, Aude Maugarny-Calès, Stéphane Pelletier, et al.

AND

Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum

Ben Ewen-Campen, Typhaine Comyn, Eric Vogt, et al.



Selected by Helen Zenner

Lineage recording reveals dynamics of cerebral organoid regionalization

Zhisong He, Tobias Gerber, Ashley Maynard, et al.



Selected by David Wilson, Irepan Salvador-Martinez

Sexually Dimorphic DNA Damage Responses and Mutation Avoidance in the Mouse Germline

Jordana C. Bloom, John C. Schimenti



Selected by Jennifer Ann Black

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