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Olfactory chemosensation extends lifespan through TGF-β signaling and UPR activation

Evandro A. De-Souza, Maximillian A. Thompson, Rebecca C. Taylor

Selected by 05 December 2022

Chee Kiang Ewe

Animal Behavior and Cognition

Deterministic and probabilistic fate decisions co-exist in a single retinal lineage

Elisa Nerli, Jenny Kretzschmar, Tommaso Bianucci, et al.

Selected by 15 November 2022

Laura Celotto

Developmental Biology

Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP

James Chapman, Hanna Salmonowicz, Stella Victorelli, et al.

Selected by 19 July 2022

Roberto Amadio

Cell Biology

State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold

James P. Roney, Sergey Ovchinnikov

Selected by 13 April 2022

Kieran Didi

Bioinformatics

Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response

Johanna L. Mehl, Ashley Earle, Jan Lammerding, et al.

Selected by 05 April 2022

Roberto Amadio

Biochemistry

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan

Selected by 09 December 2020

Connor Rosen

Immunology

Synthetic mammalian signaling circuits for robust cell population control

Yitong Ma, Mark W. Budde, Michaëlle N. Mayalu, et al.

Selected by 03 November 2020

Pavithran Ravindran

Synthetic Biology

Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion

Anh Phuong Le, Jean-François Rupprecht, René-Marc Mège, et al.

Selected by 23 September 2020

Jessica L. Teo

Cell Biology

Small molecules exploiting structural differences within microRNA-200 precursors family members reverse a type 2 diabetes phenotype

Hafeez S. Haniff, Xiaohui Liu, Laurent Knerr, et al.

Selected by 25 August 2020

Zhang-He Goh

Pharmacology and Toxicology

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, et al.

Selected by 14 July 2020

Louise Fraser

Immunology

Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival

Paolo Armando Gagliardi, Maciej Dobrzyński, Marc-Antoine Jacques, et al.

Selected by 13 July 2020

Mariana De Niz

Cell Biology

A hydraulic instability drives the cell death decision in the nematode germline

N. T. Chartier, A. Mukherjee, J. Pfanzelter, et al.

Selected by 08 July 2020

Mariana De Niz

Developmental Biology