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Promoter-intrinsic and local chromatin features determine gene repression in lamina-associated domains

Christ Leemans, Marloes van der Zwalm, Laura Brueckner, et al.

Selected by 28 November 2018

Carmen Adriaens, Clarice Hong

The Toll pathway inhibits tissue growth and regulates cell fitness in an infection-dependent manner

Federico Germani, Daniel Hain, Denise Sternlicht, et al.

Selected by 24 November 2018

Rohan Khadilkar

Cell Biology

Rapid embryonic cell cycles defer the establishment of heterochromatin by Eggless/SetDB1 in Drosophila

Charles A Seller, Chun-Yi Cho, Patrick H O'Farrell

Selected by 22 November 2018

Gabriel Aughey

Developmental Biology

A direct selection strategy for isolating aptamers with pH-sensitive binding activity

Chelsea K L Gordon, Michael Eisenstein, H T Soh

Selected by 14 November 2018

Zhang-He Goh

Synthetic Biology

Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem cells

Shumin Xia, Evelyn K.F. Yim, Pakorn Kanchanawong

AND

Superresolution architecture of pluripotency guarding adhesions

Aki Stubb, Camilo Guzmán, Elisa Närvä, et al.

Selected by 02 November 2018

Nicola Stevenson, Amanda Haage

Cell Biology

Bridging the divide: bacteria synthesizing archaeal membrane lipids

Laura Villanueva, F. A. Bastiaan von Meijenfeldt, Alexander B. Westbye, et al.

AND

Extensive transfer of membrane lipid biosynthetic genes between Archaea and Bacteria

Gareth A. Coleman, Richard D. Pancost, Tom A. Williams

Selected by 21 October 2018

Dey Lab

Cell Biology

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.

Selected by 09 October 2018

Carmen Adriaens

Genetics

3D Tissue elongation via ECM stiffness-cued junctional remodeling

Dong-Yuan Chen, Justin Crest, Sebastian J Streichan, et al.

Selected by 01 October 2018

Sundar Naganathan

Biophysics

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Silvia Bonàs-Guarch, Inês Cebola, et al.

Selected by 20 September 2018

Carmen Adriaens

Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division

Matthew L Howell, Alena Aliashkevich, Kousik Sundararajan, et al.

Selected by 20 September 2018

Hannah Behrens

Microbiology

Memory sequencing reveals heritable single cell gene expression programs associated with distinct cellular behaviors

Sydney M Shaffer, Benjamin L Emert, Ann E. Sizemore, et al.

Selected by 11 September 2018

Leighton Daigh

Cancer Biology

Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans

Kerstin Klinkert, Nicolas Levernier, Peter Gross, et al.

AND

Centrosome Aurora A gradient ensures a single PAR-2 polarity axis by regulating RhoGEF ECT-2 localization in C. elegans embryos

Sachin Kotak, Sukriti Kapoor

Selected by 09 September 2018

Giuliana Clemente

Cell Biology