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A high-coverage genome from a 200,000-year-old Denisovan

Stéphane Peyrégne, Diyendo Massilani, Yaniv Swiel, et al.

AND

A global map for introgressed structural variation and selection in humans

PingHsun Hsieh, Natthapon Soisangwan, David S. Gordon, et al.

Discussion

Post-translational Tuning of Human Cortical Progenitor Neuronal Output

Julien Pigeon, Tamina Dietl, Myriame Abou Mrad, et al.

Dissecting Gene Regulatory Networks Governing Human Cortical cell Fate

Jingwen W. Ding, Chang N. Kim, Megan S. Ostrowski, et al.

Beyond venomous fangs: Uloboridae spiders have lost their venom but not their toxicity

Xiaojing Peng, Ludwig Dersch, Josephine Dresler, et al.

Human single-cell atlas analysis reveals heterogeneous endothelial signaling

Zimo Zhu, Rongbin Zheng, Yang Yu, et al.

Discussion

High-throughput single-cell CRISPRi screens stratify neurodevelopmental functions of schizophrenia-associated genes

Umut Yildiz, Annique Claringbould, Mikael Marttinen, et al.

Discussion

Explosive cytotoxicity of ‘ruptoblasts’ bridges hormonal surveillance and immune defense

Chew Chai, Eliya Sultan, Souradeep R. Sarkar, et al.

There and back again: the dynamic evolution of panarthropod germ cell specification mechanisms

Jonchee A. Kao, Emily L. Rivard, Rishabh R. Kapoor, et al.

Discussion

TAM receptors control actomyosin dynamics in osteoclasts via RHOA-COFILIN-MYOSIN II signaling

Janik Engelmann, Jennifer Zarrer, Max Schmerder, et al.

Discussion

lineage domains and cytoskeletal cables organize a cellular square grid in a crustacean

Beatrice L. Steinert, Leo Blondel, Chandrashekar Kuyyamudi, et al.

TET knockout cells transit between pluripotent states and exhibit precocious germline entry

Raphaël Pantier, Elisa Barbieri, Sara Gonzalez Brito, et al.

Early resident NK cell response to local HIV infection in lymphoid tissue

David Perea, Alba Gonzalez, Nerea Sanchez-Gaona, et al.

Discussion