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Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, et al.

Selected by 13 February 2025

Roberto Amadio

Biochemistry

Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neurons

Klaudia Strucinska, Parker Kneis, Travis Pennington, et al.

Selected by 11 February 2025

Felipe Del Valle Batalla

Cell Biology

IMMClock reveals immune aging and T cell function at single-cell resolution

Yael Gurevich Schmidt, Di Wu, Sanna Madan, et al.

Selected by 19 January 2025

Jessica Chevallier

Bioinformatics

Germplasm stability in zebrafish requires maternal Tdrd6a and Tdrd6c

Alessandro Consorte, Yasmin El Sherif, Fridolin Kielisch, et al.

Selected by 13 December 2024

Justin Gutkowski

Developmental Biology

New evidence for the presence and function of phosphoinositides (PPIs) in the chloroplast

Mastoureh Sedaghatmehr, Frieda Rößler, Alexander P. Hertle

Selected by 12 December 2024

Shreya Pramanik

Plant Biology

Leukocytes use endothelial membrane tunnels to extravasate the vasculature

Werner J. van der Meer, Abraham C.I. van Steen, Eike Mahlandt, et al.

Selected by 08 December 2024

Felipe Del Valle Batalla

Cell Biology

Circadian modulation of mosquito host-seeking persistence by Pigment-Dispersing Factor impacts daily biting patterns

Linhan Dong, Richard Hormigo, Jord M. Barnett, et al.

Selected by 29 November 2024

Javier Cavieres

Neuroscience

cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis

Joshua Hawley, Robert Lea, Veronica Biga, et al.

Selected by 15 November 2024

Ankita Walvekar

Developmental Biology

Long range mutual activation establishes Rho and Rac polarity during cell migration

Henry De Belly, Andreu Fernandez Gallen, Evelyn Strickland, et al.

Selected by 22 October 2024

Vibha SINGH

Cell Biology

Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration

Alice E Mortimer, Adam J Reid, Raman M Das

Selected by 15 October 2024

Vibha SINGH

Cell Biology

Non-disruptive inducible labeling of ER-membrane contact sites using the Lamin B Receptor

Laura Downie, Nuria Ferrandiz, Megan Jones, et al.

Selected by 15 October 2024

Jonathan Townson

Cell Biology

HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

Estefania Sanchez-Vasquez, Marianne E. Bronner, Magdalena Zernicka-Goetz

Selected by 11 October 2024

Anchel De Jaime Soguero

Developmental Biology