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Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRASG12C suppresses PI3Kα and leads to potent tumor inhibition

Katherine Parker, Samar Ghorbanpoor, Wafa Malik, et al.

Selected by 03 June 2026

Luis Luna Ramírez

Cancer Biology

Deep Invaginations of Nuclear Envelope Coordinate Spatial Organization of Chromatin in Epithelium

Elina Mäntylä, Sanna Korpela, Anna Rekonen, et al.

Selected by 02 June 2026

Abby Hein

Cell Biology

Cardiac-immune microniches programme macrophage states in the regenerating heart

Ehsan Razaghi, Selin Tüzüner, Trishalee Gungoosingh, et al.

Selected by 19 May 2026

Theodora Stougiannou

Cell Biology

The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

Madalena Vaz Santos, Bauke V. Schomakers, Llobet Ayala Marta, et al.

Selected by 19 May 2026

Alan Leung

Developmental Biology

Small Molecule Agonists of TREM2 Reprogram Microglia and Protect Synapses in Human Alzheimer’s Models

Hossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.

Selected by 17 March 2026

Dina Kabbara

Pharmacology and Toxicology

The lipidomic architecture of the mouse brain

Luca Fusar Bassini, Halima Hannah Schede, Laura Capolupo, et al.

Selected by 09 February 2026

CRM UoE Journal Club et al.

Neuroscience

Tissue mechanics and systemic signaling safeguard epithelial tissue against spindle misorientation

Floris Bosveld, Baptiste Tesson, Eric van Leen, et al.

Selected by 26 January 2026

Ruoheng Li

Developmental Biology

Active flows drive clustering and sorting of membrane components with differential affinity to dynamic actin cytoskeleton

Abrar Bhat, Amit Das, Meenakshi Iyer, et al.

Selected by 26 January 2026

Teodora Piskova

Biophysics

A Novel Chimeric Antigen Receptor (CAR) - Strategy to Target EGFRVIII-Mutated Glioblastoma cells via Macrophages

Kristi Vera, Gülen Esken, Jin Wook Hwang, et al.

Selected by 21 January 2026

Dina Kabbara

Cancer Biology

KANK2 at focal adhesion regulates their maintenance and dynamics, while at fibrillar adhesions it influences cell migration via microtubule-dependent mechanism

Nikolina Stojanović, Anja Rac, Marija Lončarić, et al.

Selected by 12 January 2026

Vibha SINGH

Cell Biology

Taxane-Induced Conformational Changes in the Microtubule Lattice Activate GEF-H1-Dependent RhoA signaling

Joyce C. M. Meiring, Varsha Mahapatra, Molly S.C. Gravett, et al.

Selected by 31 December 2025

Vibha SINGH

Cell Biology

PIP5K-Ras bistability triggers plasma membrane symmetry breaking to define cellular polarity and regulate migration

Yu Deng, Tatsat Banerjee, Satomi Matsuoka, et al.

Selected by 29 December 2025

Vibha SINGH

Cell Biology