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Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter- and intrapatient drug responses

Chris J. de Witte, Jose Espejo Valle-Inclan, Nizar Hami, et al.

Selected by 31 December 2019

Zhang-He Goh

Pharmacology and Toxicology

Pick-ya actin: A method to purify actin isoforms with bespoke key post-translational modifications

Tomoyuki Hatano, Lavanya Sivashanmugam, Andrejus Suchenko, et al.

Selected by 19 December 2019

Angika Basant

Biochemistry

BIAFLOWS: A collaborative framework to benchmark bioimage analysis workflows

Ulysse Rubens, Romain Mormont, Volker Baecker, et al.

Selected by 29 November 2019

Mariana De Niz

Cell Biology

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal A. Samarasinghe, Osvaldo A. Miranda, Simon Mitchell, et al.

Selected by 25 November 2019

Theresa Pohlkamp

Neuroscience

Oxygenation properties of hemoglobin and the evolutionary origins of isoform multiplicity in an amphibious air-breathing fish, the blue-spotted mudskipper (Boleophthalmus pectinirostris)

Jay F. Storz, Chandrasekhar Natarajan, Magnus K. Grouleff, et al.

Selected by 04 November 2019

Charlotte Nelson

Evolutionary Biology

Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity

Alexandre Prola, Jordan Blondelle, Aymeline Vandestienne, et al.

Selected by 04 November 2019

Pablo Ranea Robles

A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses

Irina A. Okkelman, Nuno Neto, Dmitri B. Papkovsky, et al.

Selected by 30 October 2019

Jessica Xie

Cell Biology

Variant antigen diversity in Trypanosoma vivax is not driven by recombination

Sara Silva Pereira, Kayo J. G. de Almeida Castilho Neto, Craig W. Duffy, et al.

Selected by 21 October 2019

Mariana De Niz

Bioinformatics

The enteric nervous system of the human and mouse colon at a single-cell resolution

Eugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, et al.

Selected by 07 October 2019

Jessica Xie

Genomics

COMET: A toolkit for composing customizable genetic programs in mammalian cells

Patrick S. Donahue, Joseph W. Draut, Joseph J. Muldoon, et al.

Selected by 29 September 2019

Zhang-He Goh

Synthetic Biology

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Selected by 17 September 2019

Joanna Cross

A novel metric reveals previously unrecognized distortion in dimensionality reduction of scRNA-Seq data

Shamus M. Cooley, Timothy Hamilton, Eric J. Deeds, et al.

Selected by 16 August 2019

Suraj Kannan

Bioinformatics