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The enteric nervous system of the human and mouse colon at a single-cell resolution

Eugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, et al.

Selected by 07 October 2019

Jessica Xie

Genomics

COMET: A toolkit for composing customizable genetic programs in mammalian cells

Patrick S. Donahue, Joseph W. Draut, Joseph J. Muldoon, et al.

Selected by 29 September 2019

Zhang-He Goh

Synthetic Biology

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Selected by 17 September 2019

Joanna Cross

A novel metric reveals previously unrecognized distortion in dimensionality reduction of scRNA-Seq data

Shamus M. Cooley, Timothy Hamilton, Eric J. Deeds, et al.

Selected by 16 August 2019

Suraj Kannan

Bioinformatics

Arl13b regulates Sonic Hedgehog signaling from outside primary cilia

Eduardo D. Gigante, Megan R. Taylor, Anna A. Ivanova, et al.

Selected by 15 August 2019

Alex Eve

Developmental Biology

Isolation of an archaeon at the prokaryote-eukaryote interface

Hiroyuki Imachi, Masaru K. Nobu, Nozomi Nakahara, et al.

Selected by 15 August 2019

Dey Lab

Cell Biology

A modification to the life cycle of the parasite Trypanosoma brucei

Sarah Schuster, Ines Subota, Jaime Lisack, et al.

Selected by 13 August 2019

Mariana De Niz

Cell Biology

Octopi: Open configurable high-throughput imaging platform for infectious disease diagnosis in the field

Hongquan Li, Hazel Soto-Montoya, Maxime Voisin, et al.

Selected by 12 August 2019

Mariana De Niz

Bioengineering

Estimates of genetic load in small populations suggest extensive purging of deleterious alleles

Tom van der Valk, Marc de Manuel, Tomas Marques-Bonet, et al.

Selected by 05 August 2019

Neetha Iyer

Ecology

Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays

Guillermina R. Ramirez-San Juan, Arnold J. T. M. Mathijssen, Mu He, et al.

Selected by 29 July 2019

Mariana De Niz

Biophysics

Engineering Phage Host-Range and Suppressing Bacterial Resistance Through Phage Tail Fiber Mutagenesis

Kevin Yehl, Sébastien Lemire, Andrew C. Yang, et al.

Selected by 27 July 2019

Zhang-He Goh

Synthetic Biology

Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth

Erin N. Howe, Miranda D. Burnette, Melanie E. Justice, et al.

Selected by 19 July 2019

Beverley Wilson

Biochemistry