An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens
Selected by
Lorenzo Lafranchi
Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation
Selected by
Eric McGregor
Selectivity of Protein Interactions along the Aggregation Pathway of α-Synuclein
Selected by
Utrecht Protein Folding and Assembly
Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones
Selected by
Utrecht Protein Folding and Assembly
CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice
Selected by
Kristina Kuhbandner
Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis
Selected by
Madhuja Samaddar
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing
Selected by
Katie Weiner
Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors
Selected by
Sandra Malmgren Hill
Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations
Selected by
Tessa Sinnige
Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation
Selected by
Sandra Franco Iborra
HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa
Selected by
Tessa Sinnige
Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid
Selected by
Joanna Cross