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Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur

Selected by 04 December 2023

Matthew Davies

Cell Biology

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by 29 November 2023

Benjamin Dominik Maier

Bioinformatics

A Window into Mammalian Basement Membrane Development: Insights from the mTurq2-Col4a1 Mouse Model

Rebecca A. Jones, Brandon Trejo, Parijat Sil, et al.

Selected by 30 October 2023

Uwe Töpfer

Developmental Biology

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.

Selected by 26 October 2023

Hellen Costa, Marcus Oliveira

Biochemistry

Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions

Mrityunjoy Kar, Laura T. Vogel, Gaurav Chauhan, et al.

Selected by 03 October 2023

Erich Sohn

Biochemistry

Optical Control of G-Actin with a Photoswitchable Latrunculin

Nynke A. Vepřek, Madeline H. Cooper, Laura Laprell, et al.

Selected by 14 September 2023

Zhang-He Goh

Pharmacology and Toxicology

A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks

Song Feng, James A. Sanford, Thomas Weber, et al.

Selected by 30 August 2023

Benjamin Dominik Maier

Systems Biology

Similarity metric learning on perturbational datasets improves functional identification of perturbations

Ian Smith, Petr Smirnov, Benjamin Haibe-Kains

Selected by 17 August 2023

Benjamin Dominik Maier, Anna Foix Romero

Bioinformatics

Small extracellular vesicles promote stiffness-mediated metastasis

Alexandra Sneider, Ying Liu, Bartholomew Starich, et al.

Selected by 03 August 2023

Jade Chan, yohalie kalukula

Cancer Biology

A Single Laccase Acts as a Key Component of Environmental Sensing in a Broad Host Range Fungal Pathogen

Nathaniel M. Westrick, Eddie G. Dominguez, Christina M. Hull, et al.

Selected by 16 May 2023

UofA IMB565

Microbiology

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Selected by 06 May 2023

Zhang-He Goh

Pharmacology and Toxicology

A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

Selected by 10 April 2023

Benjamin Dominik Maier

Systems Biology