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Biologically informed NeuralODEs for genome-wide regulatory dynamics

Intekhab Hossain, Viola Fanfani, John Quackenbush, et al.

Selected by 31 May 2023

Benjamin Dominik Maier

Bioinformatics

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Selected by 06 May 2023

Zhang-He Goh

Pharmacology and Toxicology

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

Selected by 07 April 2023

Benjamin Dominik Maier

Genomics

Unclearing Microscopy

Ons M’Saad, Michael Shribak, Joerg Bewersdorf

Selected by 02 March 2023

Robert Mahen

Physiology

Deterministic and probabilistic fate decisions co-exist in a single retinal lineage

Elisa Nerli, Jenny Kretzschmar, Tommaso Bianucci, et al.

Selected by 15 November 2022

Laura Celotto

Developmental Biology

PHYTOMap: Multiplexed single-cell 3D spatial gene expression analysis in plant tissue

Tatsuya Nobori, Marina Oliva, Ryan Lister, et al.

Selected by 02 September 2022

Gwendolyn K. Kirschner, Marc Somssich

Bioengineering

Multifunctional fluorophores for live-cell imaging and affinity capture of proteins

Pratik Kumar, Jason D. Vevea, Edwin R. Chapman, et al.

Selected by 19 August 2022

Zhang-He Goh

Cell Biology

Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

Anoop Singh Chauhan, Alexander J. Garvin, Mohammed Jamshad, et al.

Selected by 20 June 2022

Pierre Caron

Biochemistry

Multisite imaging of neural activity using a genetically encoded calcium sensor in the honey bee Apis mellifera

Julie Carcaud, Marianne Otte, Bernd Grünewald, et al.

Selected by 23 May 2022

Lukas Weiss

Neuroscience

All-optical visualization of specific molecules in the ultrastructural context of brain tissue

Ons M’Saad, Ravikiran Kasula, Ilona Kondratiuk, et al.

Selected by 06 May 2022

Nadja Hümpfer

Neuroscience

State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold

James P. Roney, Sergey Ovchinnikov

Selected by 13 April 2022

Kieran Didi

Bioinformatics

Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine

Madeline E. Kavanagh, Benjamin D. Horning, Roli Khattri, et al.

Selected by 13 March 2022

Zhang-He Goh

Pharmacology and Toxicology