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Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells

Yun-Kyo Kim, Miguel Ramalho-Santos



Selected by Vanessa Luzak

Rapid redistribution and extensive binding of NANOG and GATA6 at shared regulatory elements underlie specification of divergent cell fates

Joyce J. Thompson, Daniel J. Lee, Apratim Mitra, et al.



Selected by María Mariner-Faulí

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

Priyanka Verma, Yeqiao Zhou, Zhendong Cao, et al.



Selected by Giuseppina D'Alessandro

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.



Selected by Osvaldo Contreras, Alexander Ward

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

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Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose



Selected by Gabriel Aughey

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.



Selected by Kirsty Ferguson

Differential regulation of lineage commitment in human and mouse primed pluripotent stem cells by NuRD

Ramy Ragheb, Sarah Gharbi, Julie Cramard, et al.



Selected by Gabriel Aughey

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation

Jasmine Li, Kristine Hardy, Moshe Olshansky, et al.



Selected by Jonny Coates

The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.



Selected by Nicola Stevenson

Co-Stimulation–Induced AP-1 Activity is Required for chromatin Opening During T Cell Activation

Masashi Yukawa, Sajjeev Jagannathan, Andrey V. Kartashov, et al.



Selected by Jonny Coates

Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals

George E Gentsch, Thomas Spruce, Nick D L Owens, et al.



Selected by Claire Simon & Sophie Morgani

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