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The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.

Selected by Audrey Noireterre

Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis

Camille Gelot, Marton Tibor Kovacs, Simona Miron, et al.

Selected by Pierre Caron

Phospho-seq: Integrated, multi-modal profiling of intracellular protein dynamics in single cells

John D. Blair, Austin Hartman, Fides Zenk, et al.

Selected by Benjamin Dominik Maier

Alumni

Mitotic heritability of DNA methylation at intermediately methylated sites is imprecise

Amir D. Hay, Noah J. Kessler, Daniel Gebert, et al.

Selected by Samantha Seah et al.

CTCF is essential for proper mitotic spindle structure and anaphase segregation

Katherine Chiu, Yasmin Berrada, Nebiyat Eskndir, et al.

Selected by Saanjbati Adhikari

Conserved Chamber-Specific Polyploidy Maintains Heart Function in Drosophila

Archan Chakraborty, Nora G. Peterson, Juliet S. King, et al.

Selected by Anastasia Moraiti

Insm1 regulates the development of mTECs and immune tolerance

Wehuai Tao, Yiqiu Wei, Zhihuan Ye, et al.

Selected by Marina Schernthanner, Jessica Chevallier

Alumni

A transcriptional and regulatory map of mouse somitogenesis

Ximena Ibarra-Soria, Elodie Thierion, Gi Fay Mok, et al.

Selected by Sergio Menchero

3D genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, et al.

Selected by Diego Martínez

Transcriptional units form the elementary constraining building blocks of the bacterial chromosome

Amaury Bignaud, Charlotte Cockram, Eric Allemand, et al.

Selected by Jennifer Ann Black

Nuclear myosin VI maintains replication fork stability

Jie Shi, Kristine Hauschulte, Ivan Mikicic, et al.