Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
Selected by
Josie Gibson, Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
Zhang-He Goh, Josie Gibson
PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome
Selected by
Andrea Irazoki
Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism
Selected by
Zhang-He Goh
Combinatorial patterns of graded RhoA activation and uniform F-actin depletion promote tissue curvature
Selected by
Grace Lim
Yeast FIT2 homolog is necessary to maintain cellular proteostasis by regulating lipid homeostasis
Selected by
Madhuja Samaddar
RAD50 promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes
Selected by
Jennifer Ann Black
The WD and linker domains of ATG16L1 required for non-canonical autophagy limit lethal influenza A virus infection at epithelial surfaces
Selected by
Kirsty Hooper
Variant antigen diversity in Trypanosoma vivax is not driven by recombination
Selected by
Mariana De Niz
Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid
Selected by
Joanna Cross
A modification to the life cycle of the parasite Trypanosoma brucei
Selected by
Mariana De Niz
Cholesterol and matrisome pathways dysregulated in human APOE ε4 glia
Selected by
Theresa Pohlkamp