Mechanosensitive dynamics of lysosomes regulates the emergence of leader cells during collective cell migration
Selected by
Jade Chan
Pseudomonas aeruginosa contracts mucus to rapidly form biofilms in tissue-engineered human airways
Selected by
Snehal Kadam
Selective inhibitors of JAK1 targeting a subtype-restricted allosteric cysteine
Selected by
Zhang-He Goh
Neuronal activity drives pathway-specific depolarization of astrocyte distal processes
Selected by
Kristina Kuhbandner
Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner
Selected by
Emma Wilson
The mechanism of artemisinin resistance of Plasmodium falciparum malaria parasites originates in their initial transcriptional response
Selected by
Victoria Alonso
Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes
Selected by
Leonor Keating
Sick Bats Stay Home Alone: Social distancing during the acute phase response in Egyptian fruit bats (Rousettus aegyptiacus)
Selected by
Baheerathan Murugavel
Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes
Selected by
Jennifer Ann Black
A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic
AND
Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
Selected by
Yen-Chung Chen
Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages
Selected by
Josie Gibson, Zhang-He Goh
Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen
AND
Tamoxifen reduces inflammatory infiltration of neutrophils in the airways
Selected by
Zhang-He Goh, Josie Gibson