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Light-microscopy based dense connectomic reconstruction of mammalian brain tissue

Mojtaba R. Tavakoli, Julia Lyudchik, Michał Januszewski, et al.

Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin

Kathryn E. Woods, Sana Akhter, Blanca Rodriguez, et al.

Discussion

Temporal constraints on enhancer usage shape the regulation of limb gene transcription

Raquel Rouco, Antonella Rauseo, Guillaume Sapin, et al.

Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma

Yoshiaki Yasumizu, Makoto Kinoshita, Martin Jinye Zhang, et al.

Discussion

Holimap: an accurate and efficient method for solving stochastic gene network dynamics

Chen Jia, Ramon Grima

A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development

Ya’el Courtney, Joshua P. Head, Elizabeth D. Yimer, et al.

Discussion

Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity

Jonathan Kuhn, Parijat Banerjee, Andrew Haye, et al.

Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2

Chrystian Junqueira Alves, Theodore Hannah, Sita Sadia, et al.

Plant plasmodesmata bridges form through ER-driven incomplete cytokinesis

Ziqiang P. Li, Hortense Moreau, Jules D. Petit, et al.

AND

Plasmodesmata act as unconventional membrane contact sites regulating inter-cellular molecular exchange in plants

Jessica Pérez-Sancho, Marija Smokvarska, Marie Glavier, et al.

Inferring protein from mRNA concentrations using convolutional neural networks

Patrick Maximilian Schwehn, Pascal Falter-Braun

Inference of drug off-target effects on cellular signaling using Interactome-Based Deep Learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette A.I. Johnson, Genevieve L. Stein-O’Brien, Max Booth, et al.

Discussion