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A data-driven Boolean model explains memory subsets and evolution in CD8+ T cell exhaustion

Geena V. Ildefonso, Stacey D. Finley

State-of-the-Art Estimation of Protein Model Accuracy using AlphaFold

James P. Roney, Sergey Ovchinnikov

Deep Learning Enables Individual Xenograft Cell Classification in Histological Images by Analysis of Contextual Features

Quentin Juppet, Fabio De Martino, Martin Weigert, et al.

Discussion

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Discussion

Subthreshold Voltage Analysis Demonstrates Neuronal Cell-Surface Sialic Acids Modulate Excitability and Network Integration

Rishikesh U. Kulkarni, Catherine L. Wang, Carolyn R. Bertozzi

ZeroCostDL4Mic: an open platform to simplify access and use of Deep-Learning in Microscopy

Lucas von Chamier, Johanna Jukkala, Christoph Spahn, et al.

Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation

Farhan Ali, Ling-Xiao Shao, Danielle M. Gerhard, et al.

Growth factor-mediated coupling between lineage size and cell fate choice underlies robustness of mammalian development

Néstor Saiz, Laura Mora-Bitria, Shahadat Rahman, et al.

Species-specific oscillation periods of human and mouse segmentation clocks are due to cell autonomous differences in biochemical reaction parameters

Mitsuhiro Matsuda, Hanako Hayashi, Jordi Garcia-Ojalvo, et al.

Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies

Candice Gurbatri, Courtney Coker, Taylor E. Hinchliffe, et al.

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Programmable bacteria induce durable tumor regression and systemic antitumor immunity

Sreyan Chowdhury, Taylor E Hinchliffe, Samuel Castro, et al.

Discussion

Short-range interactions govern cellular dynamics in microbial multi-genotype systems

Alma Dal Co, Simon van Vliet, Daniel Johannes Kiviet, et al.

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Rapid microbial interaction network inference in microfluidic droplets

Ryan H Hsu, Ryan L Clark, Jin Wei Tan, et al.

Discussion

Reconstruction of the global neural crest gene regulatory network in vivo

Ruth M Williams, Ivan Candido-Ferreira, Emmanouela Repapi, et al.

Discussion