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Bromodomain Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV2 Infection in Pre-Clinical Models

Richard J Mills, Sean J Humphrey, Patrick RJ Fortuna, et al.

Transient Maternal IL-6 boosts glutamatergic synapses and disrupts hippocampal connectivity in the offspring

Filippo Mirabella, Genni Desiato, Sara Mancinelli, et al.

Accelerated erythrocyte senescence causes dose-limiting anemia of antimalarial enolase inhibitors

Andrew J. Jezewski, Yu-Hsi Lin, Julie A. Reisz, et al.

The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors

Moheb Ghobrial, Jason Charish, Shigeki Takada, et al.

Open Science Saves Lives: Lessons from the covid-19 Pandemic

Lonni Besançon, Nathan Peiffer-Smadja, Corentin Segalas, et al.

Hydroxychloroquine increased psychiatric-like behaviors and disrupted the expression of related genes in the mouse brain

H Xu, XY Zhang, WW Wang, et al.

SARS-CoV-2 infects brain choroid plexus and disrupts the blood-CSF-barrier

Laura Pellegrini, Anna Albecka, Donna L. Mallery, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the covid-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

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Anti-SARS-CoV-2 IgG from severely ill covid-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Transcription repressor protein ZBTB25 interacts with HDAC1 in macrophages infected with Mycobacterium tuberculosis, and its inhibition leads to autophagy and killing of the intracellular pathogen

Aravind Madhavan, K B Arun, Akhil Raj Pushparajan, et al.

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Tamoxifen reduces inflammatory infiltration of neutrophils in the airways

Agustín Mansilla, Jaime Soto, Claudio Henríquez, et al.

A systematic examination of preprint platforms for use in the medical and biomedical sciences setting

Jamie J Kirkham, Naomi Penfold, Fiona Murphy, et al.

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity

Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, et al.

Broad-spectrum antivirals of protoporphyrins inhibit the entry of highly pathogenic emerging viruses

Shengsheng Lu, Xiaoyan Pan, Daiwei Chen, et al.