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A transient crispr/Cas9 expression system for genome editing in Trypanosoma brucei.

Sebastian Shaw, Sebastian Knüsel, Sarah Hoenner, et al.

Selected by 09 May 2020

Mariana De Niz

Molecular Biology

TMPRSS2 and TMPRSS4 mediate SARS-CoV-2 infection of human small intestinal enterocytes

Ruochen Zang, Maria F.G. Castro, Broc T. McCune, et al.

Selected by 29 April 2020

Brooke Chambers

Immunology

Parallel crispr-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

Selected by 27 April 2020

Mila Basic

Cell Biology

Dissection of the Fgf8 regulatory landscape by in vivo crispr-editing reveals extensive inter- and intra-enhancer redundancy

A. Hörnblad, K. Langenfeld, S. Bastide, et al.

Selected by 25 March 2020

Clarice Hong

Drug mechanism-of-action discovery through the integration of pharmacological and crispr screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by 20 March 2020

Georgina Sava

Cancer Biology

Programmable crispr interference for gene silencing using Cas13a in mosquitoes

Aditi Kulkarni, Wanqin Yu, Alex Moon, et al.

Selected by 12 December 2019

Yasmin Lau

GeneWalk identifies relevant gene functions for a biological context using network representation learning

Robert Ietswaart, Benjamin M. Gyori, John A. Bachman, et al.

Selected by 04 October 2019

Ramona Jühlen

Bioinformatics

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

Selected by 15 September 2019

Ankita Jha

Cell Biology

A single-cell transcriptomics crispr-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.

Selected by 11 September 2019

Sergio Menchero

Developmental Biology

Negative Regulation of Autophagy by UBA6-BIRC6–Mediated Ubiquitination of LC3

Rui Jia, Juan S. Bonifacino

Selected by 18 July 2019

Sandra Malmgren Hill

Cell Biology

Identification of a master regulator of differentiation in Toxoplasma

Benjamin S. Waldman, Dominic Schwarz, Marc H. Wadsworth II, et al.

Selected by 10 July 2019

Juan Quintana

Developmental Biology

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, et al.

Selected by 18 June 2019

Pavithran Ravindran

Bioengineering