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A deep mutational scanning platform to characterize the fitness landscape of anti-crispr proteins

Tobias Stadelmann, Daniel Heid, Michael Jendrusch, et al.

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens

Robert Coukos, David Yao, Mateo I. Sanchez, et al.

A ciliopathy complex builds distal appendages to initiate ciliogenesis

Dhivya Kumar, Addison Rains, Vicente Herranz-Pérez, et al.

Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays

Claire Simonneau, Martina Duschmalé, Alina Gavrilov, et al.

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.

ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

Priyanka Verma, Yeqiao Zhou, Zhendong Cao, et al.

Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis

Charles L. Evavold, Iva Hafner-Bratkovič, Jonathan C. Kagan

Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway

Anil Kumar Ganga, Margaret C. Kennedy, Mai E. Oguchi, et al.

High-throughput discovery and characterization of human transcriptional effectors

Josh Tycko, Nicole DelRosso, Gaelen T. Hess, et al.

Genome-wide crispri/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong, et al.

High-content Imaging-based Pooled crispr screens in Mammalian Cells

Xiaowei Yan, Nico Stuurman, Susana A. Ribeiro, et al.

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Image-based pooled whole genome crispr screening for Parkin and TFEB subcellular localization

Gil Kanfer, Shireen A. Sarraf, Yaakov Maman, et al.