A deep mutational scanning platform to characterize the fitness landscape of anti-crispr proteins
Selected by
Soni Mohapatra
A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state
Selected by
María Mariner-Faulí
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens
Selected by
Lorenzo Lafranchi
A ciliopathy complex builds distal appendages to initiate ciliogenesis
Selected by
Nicola Stevenson
Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays
Selected by
Kristina Kuhbandner
Precise genomic deletions using paired prime editing
Selected by
Fabio Liberante
ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells
Selected by
Giuseppina D'Alessandro
Downstream of gasdermin D cleavage, a Ragulator-Rag-mTORC1 pathway promotes pore formation and pyroptosis
Selected by
Connor Rosen
Rab34 GTPase mediates ciliary membrane biogenesis in the intracellular ciliogenesis pathway
Selected by
Nicola Stevenson
High-throughput discovery and characterization of human transcriptional effectors
Selected by
Clarice Hong
Genome-wide crispri/a screens in human neurons link lysosomal failure to ferroptosis
Selected by
Berrak Ugur
High-content Imaging-based Pooled crispr screens in Mammalian Cells
AND
Image-based pooled whole genome crispr screening for Parkin and TFEB subcellular localization
Selected by
Kirsty Ferguson