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STING mediates immune responses in a unicellular choanoflagellate

Arielle Woznica, Ashwani Kumar, Carolyn R. Sturge, et al.

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The STING ligand 2’3’-cGAMP induces an NF-κB-dependent anti-bacterial innate immune response in the starlet sea anemone Nematostella vectensis

Shally R. Margolis, Peter A. Dietzen, Beth M. Hayes, et al.

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens

Robert Coukos, David Yao, Mateo I. Sanchez, et al.

Enhancer-associated H3K4 methylation safeguards in vitro germline competence

Tore Bleckwehl, Giuliano Crispatzu, Kaitlin Schaaf, et al.

Genome-wide molecular recording using Live-seq

Wanze Chen, Orane Guillaume-Gentil, Riccardo Dainese, et al.

Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability

Sheldon Decombe, François Loll, Laura Caccianini, et al.

A ciliopathy complex builds distal appendages to initiate ciliogenesis

Dhivya Kumar, Addison Rains, Vicente Herranz-Pérez, et al.

Investigating receptor-mediated antibody transcytosis using Blood-Brain Barrier organoid arrays

Claire Simonneau, Martina Duschmalé, Alina Gavrilov, et al.

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.

Antiviral activity of bacterial TIR domains via signaling molecules that trigger cell death

Gal Ofir, Ehud Herbst, Maya Baroz, et al.

FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair

Brunno R. Levone, Silvia C. Lenzken, Marco Antonaci, et al.

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.