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A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.



Selected by Sergio Menchero

The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.



Selected by Nicola Stevenson

A developmental gene regulatory network for invasive differentiation of the C. elegans anchor cell

Taylor N. Medwig-Kinney, Jayson J. Smith, Nicholas J. Palmisano, et al.



Selected by Sina Knapp

Rapid discovery of synthetic DNA sequences to rewrite endogenous T cell circuits

Theodore L. Roth, P. Jonathan Li, Jasper F. Nies, et al.



Selected by Pavithran Ravindran

Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system

Rachel Lackie, Abdul Razzaq, Sali M.K. Farhan, et al.



Selected by Giuliana Clemente

Endogenous CRISPR arrays for scalable whole organism lineage tracing

James Cotterell, James Sharpe



Selected by Irepan Salvador-Martinez

Reconstruction of the global neural crest gene regulatory network in vivo

Ruth M Williams, Ivan Candido-Ferreira, Emmanouela Repapi, et al.



Selected by Hannah Brunsdon

Stable knockout and complementation of receptor expression using in vitro cell line derived reticulocytes for dissection of host malaria invasion requirements

Timothy J Satchwell, Katherine E Wright, Katy L Haydn-Smith, et al.



Selected by Alyson Smith

Target-specific precision of CRISPR-mediated genome editing

Anob M Chakrabarti, Tristan Henser-Brownhill, Josep Monserrat, et al.



Selected by Rob Hynds

CRISPR/Cas9-mediated gene deletion of the ompA gene in an Enterobacter gut symbiont impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes

Shivanand Hegde, Pornjarim Nilyanimit, Elena Kozlova, et al.



Selected by Snehal Kadam

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Silvia Bonàs-Guarch, Inês Cebola, et al.



Selected by Carmen Adriaens

Molecular recording of mammalian embryogenesis

Michelle Chan, Zachary D Smith, Stefanie Grosswendt, et al.



Selected by Hannah Brunsdon
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