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Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds

Jason Ioannidis, Gunes Taylor, Debiao Zhao, et al.

Selected by 14 October 2020

Martin Estermann

Developmental Biology

Generating single-sex litters: development of crispr-cas9 genetic tools to produce all-male offspring

Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, et al.

Selected by 07 October 2020

Martin Estermann

Developmental Biology

In response to Li et al.: Linker histones function in Drosophila embryogenesis

Albert Carbonell, Lazslo Henn, Juan Pérez-Roldán, et al.

Selected by 29 September 2020

Sree Rama Chaitanya

Molecular Biology

Frizzled-dependent Planar Cell Polarity without Wnt Ligands

Joyce J.S. Yu, Aude Maugarny-Calès, Stéphane Pelletier, et al.

AND

Wnt ligands are not required for planar cell polarity in the Drosophila wing or notum

Ben Ewen-Campen, Typhaine Comyn, Eric Vogt, et al.

Selected by 10 August 2020

Helen Zenner

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins

Selected by 22 May 2020

Kirsty Ferguson

Developmental Biology

Parallel crispr-cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

Selected by 27 April 2020

Mila Basic

Cell Biology

The Taste of Blood in Mosquitoes

Veronica Jové, Zhongyan Gong, Felix J.H. Hol, et al.

Selected by 23 April 2020

Vaibhav Menon

Animal Behavior and Cognition

Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens

Emanuel Gonçalves, Aldo Segura-Cabrera, Clare Pacini, et al.

Selected by 20 March 2020

Georgina Sava

Cancer Biology

Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes

Aditi Kulkarni, Wanqin Yu, Alex Moon, et al.

Selected by 12 December 2019

Yasmin Lau

Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D

Tadamoto Isogai, Kevin M. Dean, Philippe Roudot, et al.

Selected by 15 September 2019

Ankita Jha

Cell Biology

A single-cell transcriptomics CRISPR-activation screen identifies new epigenetic regulators of zygotic genome activation

Celia Alda-Catalinas, Danila Bredikhin, Irene Hernando-Herraez, et al.

Selected by 11 September 2019

Sergio Menchero

Developmental Biology

The histone chaperone FACT induces Cas9 multi-turnover behavior and modifies genome manipulation in human cells

Alan S. Wang, Leo Chen, R. Alex Wu, et al.

Selected by 20 August 2019

Nicola Stevenson

Molecular Biology