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Multi-color single molecule imaging uncovers extensive heterogeneity in mRNA decoding

Sanne Boersma, Deepak Khuperkar, Bram M.P. Verhagen, et al.

AND

Live-cell single RNA imaging reveals bursts of translational frameshifting

Kenneth R Lyon Jr, Luis U Aguilera, Tatsuya Morisaki, et al.

Selected by 18 December 2018

Nicola Stevenson

Biochemistry

Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions

Ruensern Tan, Aileen J. Lam, Tracy Tan, et al.

AND

Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

Valerie Siahaan, Jochen Krattenmacher, Amayra Hernandez-Vega, et al.

Selected by 12 December 2018

Satish Bodakuntla

Cell Biology

The modular mechanism of chromocenter formation in Drosophila

Madhav Jagannathan, Ryan Cummings, Yukiko M Yamashita

Selected by 11 December 2018

Maiko Kitaoka

Cell Biology

Molecularly distinct models of zebrafish Myc-induced B cell leukemia

Chiara Borga, Clay Foster, Sowmya Iyer, et al.

Selected by 03 December 2018

Hannah Brunsdon

Cancer Biology

Promoter-intrinsic and local chromatin features determine gene repression in lamina-associated domains

Christ Leemans, Marloes van der Zwalm, Laura Brueckner, et al.

Selected by 28 November 2018

Carmen Adriaens, Clarice Hong

Refolding activity of bacterial Hsp90 in vivo reveals ancient chaperoning function

Tania Moran Luengo, Toveann Ahlnas, Anna T. Hoekstra, et al.

Selected by 22 November 2018

Tessa Sinnige

Biochemistry

Actomyosin-driven tension at compartmental boundaries orients cell division independently of cell geometry in vivo

Elena Scarpa, Cedric Finet, Guy Blanchard, et al.

Selected by 05 November 2018

Ivana Viktorinová

Cell Biology

Signaling dynamics control cell fate in the early Drosophila embryo

Heath E Johnson, Stanislav Y Shvartsman, Jared E Toettcher

Selected by 18 October 2018

Yara E. Sánchez Corrales

Cell Biology

Three-dimensional tissue stiffness mapping in the mouse embryo supports durotaxis during early limb bud morphogenesis

Min Zhu, Hirotaka Tao, Mohammad Samani, et al.

Selected by 15 October 2018

Natalie Dye

Biophysics

Target-specific precision of CRISPR-mediated genome editing

Anob M Chakrabarti, Tristan Henser-Brownhill, Josep Monserrat, et al.

Selected by 27 September 2018

Rob Hynds

Molecular Biology

Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes

Irene Miguel-Escalada, Silvia Bonàs-Guarch, Inês Cebola, et al.

Selected by 20 September 2018

Carmen Adriaens

Incorporation of doxorubicin in different polymer nanoparticles and their anti-cancer activity

S Pieper, Hannah Onafuye, Dennis Mulac, et al.

Selected by 19 September 2018

Zhang-He Goh

Pharmacology and Toxicology