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deep learning-based predictions of gene perturbation effects do not yet outperform simple linear methods

Constantin Ahlmann-Eltze, Wolfgang Huber, Simon Anders

Selected by 11 November 2024

Benjamin Dominik Maier

Bioinformatics

Enhancer-driven cell type comparison reveals similarities between the mammalian and bird pallium

Nikolai Hecker , Niklas Kempynck , David Mauduit, et al.

Selected by 02 July 2024

Rodrigo Senovilla-Ganzo

Bioinformatics

Light-microscopy based dense connectomic reconstruction of mammalian brain tissue

Mojtaba R. Tavakoli, Julia Lyudchik, Michał Januszewski, et al.

Selected by 10 June 2024

Cemre Coskun

Neuroscience

A revised single-cell transcriptomic atlas of Xenopus embryo reveals new differentiation dynamics

Kseniya Petrova, Maksym Tretiakov, Aleksandr Kotov, et al.

Selected by 11 March 2024

Rachel Mckeown

Developmental Biology

learning a conserved mechanism for early neuroectoderm morphogenesis

Matthew Lefebvre, Jonathan Colen, Nikolas Claussen, et al.

Selected by 19 February 2024

Panagiotis Oikonomou

Biophysics

Modeling transcriptional profiles of gene perturbation with a deep neural network

Wenke Liu, Xuya Wang, D R Mani, et al.

Selected by 13 February 2024

Raquel Moya

Bioinformatics

Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

Rohith Krishna, Jue Wang, Woody Ahern, et al.

Selected by 24 January 2024

Saanjbati Adhikari

Bioengineering

Inferring protein from mRNA concentrations using convolutional neural networks

Patrick Maximilian Schwehn, Pascal Falter-Braun

Selected by 20 December 2023

Benjamin Dominik Maier

Bioinformatics

Inference of drug off-target effects on cellular signaling using Interactome-Based deep learning

Nikolaos Meimetis, Douglas A. Lauffenburger, Avlant Nilsson

Selected by 29 November 2023

Benjamin Dominik Maier

Bioinformatics

Similarity metric learning on perturbational datasets improves functional identification of perturbations

Ian Smith, Petr Smirnov, Benjamin Haibe-Kains

Selected by 17 August 2023

Benjamin Dominik Maier, Anna Foix Romero

Bioinformatics

The landscape of biomedical research

Rita González-Márquez, Luca Schmidt, Benjamin M. Schmidt, et al.

AND

ChatGPT identifies gender disparities in scientific peer review

Jeroen P.H. Verharen

Selected by 16 August 2023

Reinier Prosee

Scientific Communication and Education

Leadership in PhD (LeaP): a longitudinal leadership skill building program for underrepresented biomedical research trainees

Mali D Doles, Ji Yun Kang, Linda M Scholl, et al.

Selected by 24 October 2022

Kanika Khanna

Scientific Communication and Education