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ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination deficient cells

Priyanka Verma, Yeqiao Zhou, Zhendong Cao, et al.

Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency

Ji-Hoon Lee, Seung W. Ryu, Nicolette A. Ender, et al.

SF3B1-targeted Splicing Inhibition Triggers Global Alterations in Transcriptional Dynamics and R-Loop Metabolism

Daisy Castillo-Guzman, Stella R. Hartono, Lionel A. Sanz, et al.

Intercellular telomere transfer extends T cell lifespan

Bruno Vaz, Claudia Vuotto, Salvatore Valvo, et al.

Discussion

FANCD2 Alleviates Physiologic Replication Stress in Fetal Liver HSC

Makiko Mochizuki-Kashio, Young me Yoon, Theresa Menna, et al.

Functional diversification of Ser-Arg rich protein kinases to control ubiquitin-dependent neurodevelopmental signalling

Francisco Bustos, Anna Segarra-Fas, Gino Nardocci, et al.

Amoeba predation of Cryptococcus neoformans results in pleiotropic changes to traits associated with virulence

Man Shun Fu, Livia C. Liporagi-Lopes, Samuel R. dos Santos Júnior, et al.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Discussion

Sexually Dimorphic dna damage responses and Mutation Avoidance in the Mouse Germline

Jordana C. Bloom, John C. Schimenti

Replication protein A binds RNA and promotes R-loop formation

Olga M. Mazina, Srinivas Somarowthu, Lyudmila Y. Kadyrova, et al.

Discussion

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

RAD50 promotes dna repair by homologous recombination and restrains antigenic variation in African trypanosomes

Ann-Kathrin Mehnert, Marco Prorocic, Annick Dujeancourt-Henry, et al.

Discussion