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Sexually Dimorphic dna damage responses and Mutation Avoidance in the Mouse Germline

Jordana C. Bloom, John C. Schimenti

Replication protein A binds RNA and promotes R-loop formation

Olga M. Mazina, Srinivas Somarowthu, Lyudmila Y. Kadyrova, et al.

Discussion

Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance

Anne Ramsay Bowden, David A. Morales Juarez, Matylda Sczaniecka-Clift, et al.

RAD50 promotes dna repair by homologous recombination and restrains antigenic variation in African trypanosomes

Ann-Kathrin Mehnert, Marco Prorocic, Annick Dujeancourt-Henry, et al.

Discussion

NINJA: an inducible genetic model for creating neoantigens in vivo

Martina Damo, Brittany Fitzgerald, Yisi Lu, et al.

Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

Mounir El-Maï, Marta Marzullo, Inês Pimenta de Castro, et al.

Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system

Rachel Lackie, Abdul Razzaq, Sali M.K. Farhan, et al.

Tousled-like kinase activity is required for transcriptional silencing and suppression of innate immune signaling

Sandra Segura-Bayona, Marina Villamor-Payà, Camille Stephan-Otto Attolini, et al.

Discussion

PUMILIO hyperactivity drives premature aging of Norad-deficient mice

Florian Kopp, Mehmet Yalvac, Beibei Chen, et al.

Discussion

LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy

Susanne Nichterwitz, Helena Storvall, Jik Nijssen, et al.

AND

Axon-seq decodes the motor axon transcriptome and its modulation in response to ALS

Jik Nijssen, Julio Cesar Aguila Benitez, Rein Hoogstraaten, et al.

Discussion

A limited number of double-strand dna breaks are sufficient to delay cell cycle progression.

Jeroen van den Berg, Anna G. Manjon, Karoline Kielbassa, et al.

Discussion

A role for RNA and dna:RNA hybrids in the modulation of dna repair by homologous recombination

Giuseppina D'Alessandro, Marek Adamowicz, Donna Whelan, et al.

Discussion