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Absolute Scaling of Single-Cell Transcriptomes Reveals Pervasive Hypertranscription in Adult Stem and Progenitor Cells

Yun-Kyo Kim, Miguel Ramalho-Santos

Selected by 29 March 2022

Vanessa Luzak

Molecular Biology

ATM-dependent formation of a novel chromatin compartment regulates the Response to dna Double Strand Breaks and the biogenesis of translocations

Coline Arnould, Vincent Rocher, Aldo S. Bader, et al.

Selected by 17 February 2022

Jennifer Ann Black

Molecular Biology

cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, et al.

Selected by 01 February 2022

Roberto Amadio

Cell Biology

Drag-and-drop genome insertion without dna cleavage with CRISPR-directed integrases

Eleonora I. Ioannidi, Matthew T. N. Yarnall, Cian Schmitt-Ulms, et al.

Selected by 15 December 2021

Louise Moyle et al.

Genomics

The vacuolar iron transporter mediates iron detoxification in Toxoplasma gondii

Dana Aghabi, Megan Sloan, Zhicheng Dou, et al.

Selected by 19 October 2021

Jennifer Ann Black

Cell Biology

Nuclear soluble cGAS senses dna virus infection

Yakun Wu, Kun Song, Wenzhuo Hao, et al.

Selected by 16 September 2021

Roberto Amadio

Immunology

Two redundant ubiquitin-dependent pathways of BRCA1 localization to dna damage sites

Alana Sherker, Natasha Chaudhary, Salomé Adam, et al.

Selected by 10 August 2021

Giuseppina D'Alessandro

Cell Biology

The force loading rate drives cell mechanosensing through both reinforcement and fluidization

Ion Andreu, Bryan Falcones, Sebastian Hurst, et al.

Selected by 20 March 2021

Jessica L. Teo

Biophysics

Crosstalk between H2A variant-specific modifications impacts vital cell functions

Anna Schmücker, Bingkun Lei, Zdravko J. Lorković, et al.

Selected by 06 March 2021

Pravrutha Raman, Harmit Malik

Synthetic Biology

Structure of an infectious mammalian prion

Allison Kraus, Forrest Hoyt, Cindi L. Schwartz, et al.

Selected by 04 March 2021

Jennifer Ann Black

Biochemistry

FUS-dependent liquid-liquid phase separation is an early event in double-strand break repair

Brunno R. Levone, Silvia C. Lenzken, Marco Antonaci, et al.

Selected by 05 February 2021

Sree Rama Chaitanya, Giuseppina D'Alessandro

Cell Biology

A developmentally programmed splicing failure attenuates the dna damage response during mammalian zygotic genome activation

Christopher D. R. Wyatt, Barbara Pernaute, André Gohr, et al.

Selected by 05 February 2021

Sree Rama Chaitanya

Developmental Biology