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DOT1L activity affects cell lineage progression in the developing brain by controlling metabolic programs

Bismark Appiah, Camilla L. Fullio, Christiane Haffner, et al.

Selected by 26 August 2022

Laura Celotto

Developmental Biology

cGAS recruitment to micronuclei is dictated by pre-existing nuclear chromatin status

Kate M. MacDonald, Shirony Nicholson-Puthenveedu, Maha M. Tageldein, et al.

Selected by 01 February 2022

Roberto Amadio

Cell Biology

Diverse mechanisms for epigenetic imprinting in mammals

Daniel Andergassen, Zachary D. Smith, John L. Rinn, et al.

Selected by 18 June 2021

Sergio Menchero

Genetics

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

Selected by 15 June 2021

María Mariner-Faulí

Developmental Biology

Integration of Protein Interactome Networks with Congenital Heart Disease Variants Reveals Candidate Disease Genes

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, et al.

Selected by 21 April 2021

Alexander Ward

Genetics

Epigenetic rewriting at centromeric dna repeats leads to increased chromatin accessibility and chromosomal instability

Sheldon Decombe, François Loll, Laura Caccianini, et al.

Selected by 18 April 2021

Sree Rama Chaitanya

Cell Biology

m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of Toxoplasma gondii

Michael J. Holmes, Leah R. Padgett, Matheus S. Bastos, et al.

AND

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma

Dayana C. Farhat, Matthew Bowler, Guillaume Communie, et al.

Selected by 22 March 2021

Joao Mello-Vieira

Microbiology

A systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination

Desislava P. Staneva, Roberta Carloni, Tatsiana Auchynnikava, et al.

Selected by 11 March 2021

Tamara Sternlieb

Cell Biology

Crosstalk between H2A variant-specific modifications impacts vital cell functions

Anna Schmücker, Bingkun Lei, Zdravko J. Lorković, et al.

Selected by 06 March 2021

Pravrutha Raman, Harmit Malik

Synthetic Biology

Neuronal Enhancers are Hotspots For dna Single-Strand Break Repair

Wei Wu, Sarah E. Hill, William J. Nathan, et al.

Selected by 06 January 2021

Giuseppina D'Alessandro, Sree Rama Chaitanya

Cell Biology

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos

Selected by 07 August 2020

Sergio Menchero

Molecular Biology

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

AND

Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Selected by 07 August 2020

Zhang-He Goh

Pharmacology and Toxicology