The loss of dna polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity
Selected by
Audrey Noireterre
Digitize your Biology! Modeling multicellular systems through interpretable cell behavior
Selected by
Benjamin Dominik Maier et al.
Tardigrades dramatically upregulate dna repair pathway genes in response to ionizing radiation
Selected by
Isabella Cisneros
CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
Jessica Chevallier, Pierre Caron
A transposase-derived gene required for human brain development
Selected by
Amanda Ivanoff
Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of dna double strand breaks in mitosis
Selected by
Pierre Caron
EXO1-mediated dna repair by single-strand annealing is essential for BRCA1-deficient cells
Selected by
Jennifer Ann Black
Actin nucleators safeguard replication forks by limiting nascent strand degradation
Selected by
Roberto Amadio
BRCA1/BARD1 ubiquitinates PCNA in unperturbed conditions to promote replication fork stability and continuous dna synthesis
Selected by
Pierre Caron
Single-strand mismatch and damage patterns revealed by single-molecule dna sequencing
Selected by
Kerryn Elliott
Nuclear myosin VI maintains replication fork stability
Selected by
Pierre Caron
Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation
Selected by
Pierre Caron