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Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

Marinelle Rodrigues, Parastoo Sabaeifard, Muhammed Sadik Yildiz, et al.

Selected by 16 May 2023

UofA IMB565

Microbiology

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.

Selected by 06 May 2023

Zhang-He Goh

Pharmacology and Toxicology

Massively parallel protein-protein interaction measurement by sequencing (MP3-seq) enables rapid screening of protein heterodimers

Alexander Baryshev, Alyssa La Fleur, Benjamin Groves, et al.

Selected by 07 April 2023

Benjamin Dominik Maier

Genomics

A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly

Brett Volmert, Ashlin Riggs, Fei Wang, et al.

Selected by 13 February 2023

Silvia Becca

Bioengineering

An epigenetic barrier sets the timing of human neuronal maturation

Gabriele Ciceri, Hyunwoo Cho, Meghana Kshirsagar, et al.

Selected by 01 December 2022

PiCLS Dundee

Neuroscience

Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

Johanna Lilja, Jasmin Kaivola, James R.W. Conway, et al.

Selected by 23 October 2022

Yvonne Xinyi Lim

Cancer Biology

Disrupting cellular memory to overcome drug resistance

Guillaume Harmange, Raúl A. Reyes Hueros, Dylan Schaff, et al.

Selected by 18 September 2022

Nate Mullin

Cell Biology

Antimalarials in mosquitoes overcome Anopheles and Plasmodium resistance to malaria control strategies

Douglas G. , Alexandra S. , Erica, et al.

Selected by 19 August 2022

Nassif Seni, Helen Robertson

Immunology

Plakoglobin is a mechanoresponsive regulator of naïve pluripotency

Timo N. Kohler, Joachim De Jonghe, Anna L. Ellerman, et al.

Selected by 23 May 2022

Ilaria Di Meglio

Developmental Biology

Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality

Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, et al.

Selected by 08 March 2022

Emma Wilson

Neuroscience

Self-organized morphogenesis of a human neural tube in vitro by geometric constraints

Eyal Karzbrun, Aimal H. Khankhel, Heitor C. Megale, et al.

Selected by 22 September 2021

Srivatsava Viswanadha

Bioengineering

SARS-CoV-2 Variants are Selecting for Spike Protein Mutations that Increase Protein Stability

David Shorthouse, Benjamin. A. Hall

Selected by 04 August 2021

Soni Mohapatra

Biophysics