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Oncogenic hijacking of a developmental transcription factor evokes therapeutic vulnerability for ROS-induction in Ewing sarcoma

Aruna Marchetto, Shunya Ohmura, Martin F. Orth, et al.

Selected by 12 April 2019

Hannah Brunsdon

Cancer Biology

Slide-seq: A Scalable Technology for Measuring Genome-Wide Expression at High Spatial Resolution

Samuel G Rodriques, Robert R Stickels, Aleksandrina Goeva, et al.

AND

High-density spatial transcriptomics arrays for in situ tissue profiling

Sanja Vickovic, Goekcen Eraslan, Johanna Klughammer, et al.

Selected by 20 March 2019

Carmen Adriaens

Bioinformatics

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC Reprogramming

Adrian Janiszewski, Irene Talon, Juan Song, et al.

Selected by 12 March 2019

Sergio Menchero

Developmental Biology

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

Selected by 07 March 2019

Pablo Ranea Robles

Pathology

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

Sherine E. Thomas, Andrew J. Whitehouse, Karen Brown, et al.

Selected by 05 March 2019

Yasmin Lau

Inactive USP14 and inactive UCHL5 cause accumulation of distinct ubiquitinated proteins in mammalian cells

Jayashree Chadchankar, Victoria Korboukh, Peter Doig, et al.

Selected by 31 January 2019

Mila Basic

Molecular Biology

Large-scale analyses of human microbiomes reveal thousands of small, novel genes and their predicted functions

Hila Sberro, Nicholas Greenfield, Georgios Pavlopoulos, et al.

Selected by 23 January 2019

Ganesh Kadamur

Bioinformatics

Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

Jonathan P Gumucio, Austin H Qasawa, Patrick J Ferrara, et al.

Selected by 07 January 2019

Pablo Ranea Robles

Pathology

Disrupting Transcriptional Feedback Yields an Escape-Resistant Antiviral

Sonali Chaturvedi, Marie Wolf, Noam Vardi, et al.

Selected by 03 January 2019

Pavithran Ravindran

Biochemistry

development and validation of serological markers for detecting recent exposure to Plasmodium vivax infection

Rhea Jessica Longley, Michael T White, Eizo Takashima, et al.

AND

Antimalarial drug mefloquine kills both trophozoite and cyst stages of Entamoeba

Conall Sauvey, Gretchen Ehrenkaufer, Anjan Debnath, et al.

Selected by 31 December 2018

Zhang-He Goh

Pharmacology and Toxicology

Robust Antibacterial Activity of Tungsten Oxide (WO3-X) Nanodots

Guangxin Duan, Lu Chen, Zhifeng Jing, et al.

Selected by 21 December 2018

Zhang-He Goh

Pharmacology and Toxicology

Biofilm/Persister/Stationary Phase Bacteria Cause More Severe Disease Than Log Phase Bacteria II Infection with Persister Forms of Staphylococcus aureus Causes a Chronic Persistent Skin Infection with More Severe Lesion that Takes Longer to Heal and is not Eradicated by the Current Recommended Treatment in Mice

Rebecca Yee, Yuting Yuan, Cory Brayton, et al.

Selected by 20 December 2018

Snehal Kadam

Microbiology