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A spatially resolved single cell atlas of human gastrulation

Richard C.V. Tyser, Elmir Mahammadov, Shota Nakanoh, et al.

Selected by 10 September 2020

Martin Estermann

Developmental Biology

Systematic analysis of protein targets associated with adverse events of drugs from clinical trials and post-marketing reports

Ines A. Smit, Avid M. Afzal, Chad H. G. Allen, et al.

AND

Toward in vivo-relevant hERG safety assessment and mitigation strategies based on relationships between non-equilibrium blocker binding, three-dimensional channel-blocker interactions, dynamic occupancy, dynamic exposure, and cellular arrhythmia

Hongbin Wan, Gianluca Selvaggio, Robert A. Pearlstein

Selected by 13 July 2020

Zhang-He Goh

Pharmacology and Toxicology

Probing the Subcellular Distribution of Phosphatidylinositol Reveals a Surprising Lack at the Plasma Membrane

James P. Zewe, April Miller, Sahana Sangappa, et al.

AND

Defining the Subcellular Distribution and Metabolic Channeling of Phosphatidylinositol

Joshua G. Pemberton, Yeun Ju Kim, Nivedita Sengupta, et al.

Selected by 25 July 2019

Sruthi S Balakrishnan

Cell Biology

Benchmarking Single-Cell RNA Sequencing Protocols for Cell Atlas Projects

Elisabetta Mereu, Atefeh Lafzi, Catia Moutinho, et al.

AND

Systematic comparative analysis of single cell RNA-sequencing methods

Jiarui Ding, Xian Adiconis, Sean K. Simmons, et al.

Selected by 01 June 2019

Rob Hynds

Bioinformatics

Structures of the Otopetrin Proton Channels Otop1 and Otop3

Kei Saotome, Bochuan Teng, Che Chun (Alex) Tsui, et al.

Selected by 12 February 2019

David Wright

Biochemistry

Embryo geometry drives formation of robust signaling gradients through receptor localization

Zhechun Zhang, Steven Zwick, Ethan Loew, et al.

Selected by 03 January 2019

Paul Gerald L. Sanchez and Stefano Vianello

Developmental Biology

Systematic identification of human SNPs affecting regulatory element activity

Joris van Arensbergen, Ludo Pagie, Vincent FitzPatrick, et al.

Selected by 29 November 2018

Jesus Victorino

The landscape of antigen-specific T cells in human cancers

Bo Li, Longchao Liu, Jian Zhang, et al.

Selected by 19 November 2018

Rob Hynds

Cancer Biology

Quantitative, real-time, single cell analysis in tissue reveals expression dynamics of neurogenesis

Cerys S Manning, Veronica Biga, James Boyd, et al.

Selected by 09 August 2018

Teresa Rayon

Developmental Biology

Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy

Martin Weigert, Uwe Schmidt, Tobias Boothe, et al.

Selected by 22 February 2018

Uri Manor

Cell Biology