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Actin polymerization drives lumen formation in a human epiblast model

Dhiraj Indana, Andrei Zakharov, Youngbin Lim, et al.



Selected by Megane Rayer, Rivka Shapiro

Patterned embryonic invagination evolved in response to mechanical instability

Bruno C. Vellutini, Marina B. Cuenca, Abhijeet Krishna, et al.

AND

Divergent evolutionary strategies preempt tissue collision in fly gastrulation

Bipasha Dey, Verena Kaul, Girish Kale, et al.



Selected by Reinier Prosee et al.

Ancient origins of complex neuronal genes

Matthew J. McCoy, Andrew Z. Fire



Selected by Preethi Krishnaraj, Chee Kiang Ewe

Maintenance of pluripotency in the entire ectoderm enables neural crest formation

Ceren Pajanoja, Jenny Hsin, Bradley Olinger, et al.



Selected by Andrew Montequin

An improved Erk biosensor reveals oscillatory Erk dynamics driven by mitotic erasure during early development

Scott G. Wilcockson, Luca Guglielmi, Pablo Araguas Rodriguez, et al.



Selected by Sakurako Kobayashi

A specialized mRNA translation circuit instated in pluripotency presets the competence for cardiogenesis in humans

Deniz Bartsch, Kaustubh Kalamkar, Gaurav Ahuja, et al.



Selected by Emma Armitage

Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart

Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, et al.

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Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development

Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, et al.



Selected by Monica Tambalo et al.

PHYTOMap: Multiplexed single-cell 3D spatial gene expression analysis in plant tissue

Tatsuya Nobori, Marina Oliva, Ryan Lister, et al.



Selected by Gwendolyn K. Kirschner, Marc Somssich

The ELT-3 GATA factor specifies endoderm in Caenorhabditis angaria in an ancestral gene network

Gina Broitman-Maduro, Morris F. Maduro



Selected by Chee Kiang Ewe

Synthetic memory circuits for programmable cell reconfiguration in plants

James P B Lloyd, Florence Ly, Patrick Gong, et al.

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Synthetic genetic circuits enable reprogramming of plant roots

Jennifer A. N. Brophy, Katie J. Magallon, Kiril Kniazev, et al.



Selected by Gwendolyn K. Kirschner

Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Mírian Romitti, Barbara de Faria da Fonsecaa, Gilles Doumont, et al.



Selected by Anna Meier

Pseudo-dynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left-right asymmetry

Isaac Esteban, Patrick Schmidt, Susana Temiño, et al.



Selected by Yen Tran

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