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YAP1 Regulates the Self-organized Fate Patterning of hESCs-Derived Gastruloids

Servando Giraldez, Eleonora Stronati, Ling Huang, et al.

Selected by 25 June 2021

Srivatsava Viswanadha

Cell Biology

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

Selected by 15 June 2021

María Mariner-Faulí

Developmental Biology

enhancer-associated H3K4 methylation safeguards in vitro germline competence

Tore Bleckwehl, Giuliano Crispatzu, Kaitlin Schaaf, et al.

Selected by 13 May 2021

Sree Rama Chaitanya

Developmental Biology

Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth

Tomas Raul Wiche Salinas, Yuwei Zhang, Daniele Sarnello, et al.

Selected by 20 April 2021

Joao Mello-Vieira

Immunology

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.

Selected by 17 February 2021

Sergio Menchero

Molecular Biology

Precise genomic deletions using paired prime editing

Junhong Choi, Wei Chen, Chase C. Suiter, et al.

Selected by 27 January 2021

Fabio Liberante

Genomics

Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque

Paul Cheng, Robert C. Wirka, Juyong Brian Kim, et al.

Selected by 12 January 2021

Debbie Ho

Cell Biology

Neuronal enhancers are Hotspots For DNA Single-Strand Break Repair

Wei Wu, Sarah E. Hill, William J. Nathan, et al.

Selected by 06 January 2021

Giuseppina D'Alessandro, Sree Rama Chaitanya

Cell Biology

Evolution of mouse circadian enhancers from transposable elements

Julius Judd, Hayley Sanderson, Cédric Feschotte

Selected by 15 December 2020

Miguel V. Almeida

Genomics

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

Jialin Liu, Rebecca R. Viales, Pierre Khoueiry, et al.

Selected by 11 December 2020

Irepan Salvador-Martinez

Bioinformatics

Genome-wide maps of enhancer regulation connect risk variants to disease genes

Joseph Nasser, Drew T. Bergman, Charles P. Fulco, et al.

Selected by 30 September 2020

Jesus Victorino

Genomics

Orphan CpG islands boost the regulatory activity of poised enhancers and dictate the responsiveness of their target genes

Tomás Pachano, Víctor Sánchez-Gaya, María Mariner-Faulí, et al.

Selected by 07 September 2020

Jesus Victorino

Genetics