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A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Michael Alexanian, Pawel F. Przytycki, Rudi Micheletti, et al.

Discussion

CTCF Mediates Dosage and Sequence-context-dependent Transcriptional Insulation through Formation of Local Chromatin Domains

Hui Huang, Quan Zhu, Adam Jussila, et al.

An Atlas of Gene Regulatory Elements in Adult Mouse Cerebrum

Yang Eric Li, Sebastian Preissl, Xiaomeng Hou, et al.

Discussion

LINE elements are a reservoir of regulatory potential in mammalian genomes

Maša Roller, Ericca Stamper, Diego Villar, et al.

Regulation of blood cell transdifferentiation by oxygen sensing neurons

Sean Corcoran, Anjeli Mase, Yousuf Hashmi, et al.

A localization screen reveals translation factories and widespread co-translational RNA targeting

Racha Chouaib, Adham Safieddine, Xavier Pichon, et al.

Discussion

Endogenous retroviruses drive species-specific germline transcriptomes in mammals

Akihiko Sakashita, So Maezawa, Kris G. Alavattam, et al.

Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics

S Basu, O Shukron, A Ponjavic, et al.

AND

Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy

Miles K. Huseyin, Robert J. Klose

Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation

Sun Y. Maybury-Lewis, Abigail K. Brown, Mitchell Yeary, et al.

Discussion

Endogenous retroviruses are a source of enhancers with oncogenic potential in acute myeloid leukaemia

Özgen Deniz, Mamataz Ahmed, Christopher D. Todd, et al.

Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive inter- and intra-enhancer redundancy

A. Hörnblad, K. Langenfeld, S. Bastide, et al.

enhancers predominantly regulate gene expression in vivo via transcription initiation

Martin S. C. Larke, Takayuki Nojima, Jelena Telenius, et al.