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The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.



Selected by Audrey Noireterre

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.



Selected by Hellen Costa, Marcus Oliveira

NAD+ metabolism is a key modulator of bacterial respiratory epithelial infections

Björn Klabunde, André Wesener, Wilhelm Bertrams, et al.



Selected by Matheus Atella de Oliveira, Marcus Oliveira

NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, et al.



Selected by Matheus Atella de Oliveira, Marcus Oliveira

Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells

Kaitlin N Allen, Julia María Torres-Velarde, Juan Manuel Vazquez, et al.



Selected by Sarah Young-Veenstra

Mechano-dependent sorbitol accumulation supports biomolecular condensate

Stephanie Torrino, William M Oldham, Andrés R Tejedor, et al.



Selected by Teodora Piskova

Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways

Aakanksha Jain, Benjamin M. Gyori, Sara Hakim, et al.



Selected by Patrick Penndorf

DNA methylation rates scale with maximum lifespan across mammals

Samuel. J. C. Crofts, Eric Latorre-Crespo, Tamir Chandra



Selected by Jennifer Ann Black

Coxiella burnetii actively blocks IL-17-induced oxidative stress in macrophages

Tatiana M. Clemente, Leonardo Augusto, Rajendra K. Angara, et al.



Selected by UofA IMB565

A Single Laccase Acts as a Key Component of Environmental Sensing in a Broad Host Range Fungal Pathogen

Nathaniel M. Westrick, Eddie G. Dominguez, Christina M. Hull, et al.



Selected by UofA IMB565

SQ3370, the first clinical click chemistry-activated cancer therapeutic, shows safety in humans and translatability across species

Sangeetha Srinivasan, Nathan A. Yee, Michael Zakharian, et al.



Selected by Zhang-He Goh

Transcriptional units form the elementary constraining building blocks of the bacterial chromosome

Amaury Bignaud, Charlotte Cockram, Eric Allemand, et al.



Selected by Jennifer Ann Black
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