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Brazil Nut Effect Drives Pattern Formation in Early Mammalian Embryos

Zheng Guo, Jie Yao, Xu Zheng, et al.



Selected by Sophia Friesen

The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Giuliano Crispatzu, Rizwan Rehimi, Tomas Pachano, et al.



Selected by Sergio Menchero

A spatially resolved single cell atlas of human gastrulation

Richard C.V. Tyser, Elmir Mahammadov, Shota Nakanoh, et al.



Selected by Martin Estermann

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos



Selected by Sergio Menchero

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.



Selected by Pierre Osteil

Organoid Easytag: an efficient workflow for gene targeting in human organoids

Dawei Sun, Lewis D. Evans, Emma L. Rawlins



Selected by Kirsty Ferguson

Early neurulation recapitulated in assemblies of embryonic and extraembryonic cells

Noémie M. L. P. Bérenger-Currias, Maria Mircea, Esmée Adegeest, et al.



Selected by Monica Tambalo

Defining totipotency using criteria of increasing stringency

Eszter Posfai, John Paul Schell, Adrian Janiszewski, et al.



Selected by Teresa Rayon

An asymmetry in the frequency and position of mitosis in the epiblast precedes gastrulation and suggests a role for mitotic rounding in cell delamination during primitive streak epithelial-mesenchymal transition

Evangéline Despin-Guitard, Navrita Mathiah, Matthew Stower, et al.



Selected by Claire Simon & Sophie Morgani

Trophectoderm Potency is Retained Exclusively in Human Naïve Cells

Ge Guo, Giuliano Giuseppe Stirparo, Stanley Strawbridge, et al.



Selected by Sergio Menchero

DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

Barbara Pernaute, Juan Miguel Sánchez Nieto, Salvador Pérez-Montero, et al.



Selected by Katarzyna Kuzmicz-Kowalska

Differences in mitochondrial activity trigger cell competition during early mouse development

Ana Lima, Gabriele Lubatti, Jörg Burgstaller, et al.



Selected by Teresa Rayon

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