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Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models

Nalini R. Rao, Olivia DeGulis, Toshihiro Nomura, et al.

Selected by 11 January 2025

Jawdat Sandakly

Neuroscience

Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Jasmin Kaivola, Karolina Punovuori, Megan R. Chastney, et al.

Selected by 19 December 2024

Teodora Piskova

Cancer Biology

Alzheimer’s Disease Patient Brain Extracts Induce Multiple Pathologies in Vascularized Neuroimmune Organoids for Disease Modeling and Drug Discovery

Yanru Ji, Xiaoling Chen, Meek Connor Joseph, et al.

Selected by 07 November 2024

Manuel Lessi

Neuroscience

Mechano-dependent sorbitol accumulation supports biomolecular condensate

Stephanie Torrino, William M Oldham, Andrés R Tejedor, et al.

Selected by 07 September 2023

Teodora Piskova

Cell Biology

Glioblastoma extracellular vesicles influence glial cell hyaluronic acid deposition to promote invasiveness

Dominik Koessinger, David Novo, Anna Koessinger, et al.

Selected by 13 June 2023

Jade Chan

Cancer Biology

Comparative analysis of cattle breeds as satellite cell donors for cultured beef

Lea Melzener, Shijie Ding, Rui Hueber, et al.

Selected by 28 February 2022

Alexander Ward

Cell Biology

Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq

Krysta L. Engel, Hei-Yong G. Lo, Raeann Goering, et al.

Selected by 15 September 2021

Ashleigh Davey

Molecular Biology

Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

Constanze Depp, Ting Sun, Andrew Octavian Sasmita, et al.

Selected by 19 August 2021

Kristina Kuhbandner

Neuroscience

After traumatic brain injury oligodendrocytes regain a plastic phenotype and can become astrocytes

Xianshu Bai, Na Zhao, Wenhui Huang, et al.

Selected by 06 August 2021

Ranabir Chakraborty

Neuroscience

Mechanosensitivity of amoeboid cells crawling in 3D

Florian Gaertner, Patricia Reis-Rodrigues, Ingrid de Vries, et al.

Selected by 24 June 2021

Jessica L. Teo

Cancer Biology

Foldamers Reveal and Validate Novel Therapeutic Targets Associated with Toxic α-Synuclein Self-Assembly

Jemil Ahmed, Tessa C. Fitch, Courtney M. Donnelly, et al.

Selected by 05 June 2021

Joanna Zell

Biochemistry

Selectivity of Protein Interactions along the Aggregation Pathway of α-Synuclein

André D. G. Leitão, Paulina Rudolffi Soto, Alexandre Chappard, et al.

Selected by 15 April 2021

Utrecht Protein Folding and Assembly

Biochemistry