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Single-cell RNA-sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

Arun C. Habermann, Austin J. Gutierrez, Linh T. Bui, et al.

AND

Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary fibrosis

Taylor S. Adams, Jonas C. Schupp, Sergio Poli, et al.

Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection

Caroline B. Turner, Sean W. Buskirk, Katrina B. Harris, et al.

The origin of extracellular DNA in bacterial biofilm infections in vivo

Maria Alhede, Morten Alhede, Klaus Qvortrup, et al.

Discussion

Gene regulatory network inference and analysis of multidrug-resistant Pseudomonas aeruginosa

Fernando Medeiros Filho, Ana Paula Barbosa do Nascimento, Marcelo Trindade dos Santos, et al.

Discussion

Human cardiac fibrosis-on-a-chip model recapitulates disease hallmarks and can serve as a platform for drug screening

Olya Mastikhina, Byeong-Ui Moon, Kenneth Williams, et al.

Discussion

Liver-Chip: Reproducing Human and Cross-Species Toxicities

Kyung-Jin Jang, Monicah A. Otieno, Janey Ronxhi, et al.

Discussion

A Bile Duct-on-a-Chip with Organ-Level Functions

Yu Du, Gauri Khandekar, Jessica Llewellyn, et al.

Hepatocyte-specific deletion of Pparα promotes NASH in the context of obesity

Marion Regnier, Arnaud Polizzi, Sarra Smati, et al.

Dynamic Aha1 Co-Chaperone Binding to Human Hsp90

Javier Oroz, Laura J Blair, Markus Zweckstetter

Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

Jonathan P Gumucio, Austin H Qasawa, Patrick J Ferrara, et al.

Discussion

Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals

Salah Mahmoudi, Elena Mancini, Alessandra Moore, et al.

Discussion

Single-cell RNA sequencing reveals novel cell differentiation dynamics during human airway epithelium regeneration

Sandra Ruiz Garcia, Marie Deprez, Kevin Lebrigand, et al.